@charset "UTF-8";:root{--spacing-components-desktop-0:0;--spacing-components-desktop-2:2px;--spacing-components-desktop-4:4px;--spacing-components-desktop-6:6px;--spacing-components-desktop-8:8px;--spacing-components-desktop-10:8px;--spacing-components-desktop-12:8px;--spacing-components-desktop-14:8px;--spacing-components-desktop-16:10px;--spacing-components-desktop-24:12px;--spacing-components-desktop-32:16px;--spacing-components-desktop-40:24px;--spacing-section-condensed:24px;--spacing-section-normal:32px;--spacing-section-spacious:40px;--spacing-document-condensed:40px;--spacing-document-normal:60px;--spacing-document-spacious:80px;--spacing-table-cell-top-and-bottom:10px;--spacing-table-cell-left-and-right:12px;--spacing-table-header-cell-default:48px;--spacing-table-header-cell-large:64px;--spacing-button-small-top-and-bottom:8px;--spacing-button-small-left-and-right:16px;--spacing-button-small-icon-only-left-and-right:8px;--spacing-button-regular-top-and-bottom:14px;--spacing-button-regular-left-and-right:28px;--spacing-button-regular-icon-only-left-and-right:14px;--spacing-button-large-top-and-bottom:16px;--spacing-button-large-left-and-right:40px;--spacing-button-large-icon-only-left-and-right:16px;--spacing-quiz-padding-top-bottom:8px;--spacing-quiz-padding-left-right:8px;--spacing-quiz-gap:8px;--spacing-menu-item-padding:12px;--spacing-menu-item-header-inside-padding-top:0;--spacing-menu-item-header-inside-padding-bottom:0;--spacing-forms-field-height:48px;--spacing-accordions-space-between:0;--spacing-tabs-space-between-horizontal:0;--spacing-tabs-space-between-vertical:0;--spacing-tabs-tab-alt-padding:8px;--spacing-text-links-small:5px;--spacing-text-links-medium:10px;--spacing-text-links-large:12px;--typography-headings-jumbo-font-size:3.5rem;--typography-headings-jumbo-superscript-font-size:2.5199999809265137rem;--typography-headings-jumbo-superscript-leading:2.940000057220459rem;--typography-headings-jumbo-leading:4.5rem;--typography-headings-jumbo-letter-spacing:-0.0625rem;--typography-headings-headline-1-font-size:2.5rem;--typography-headings-headline-1-superscript-font-size:1.399999976158142rem;--typography-headings-headline-1-superscript-leading:1.9600000381469727rem;--typography-headings-headline-1-leading:3.5rem;--typography-headings-headline-1-letter-spacing:-0.03125rem;--typography-headings-headline-2-font-size:2rem;--typography-headings-headline-2-superscript-font-size:1.1200000047683716rem;--typography-headings-headline-2-superscript-leading:1.4700000286102295rem;--typography-headings-headline-2-leading:2.625rem;--typography-headings-headline-2-letter-spacing:-0.03125rem;--typography-headings-headline-3-font-size:1.75rem;--typography-headings-headline-3-superscript-font-size:.9800000190734863rem;--typography-headings-headline-3-superscript-leading:1.399999976158142rem;--typography-headings-headline-3-leading:2.5rem;--typography-headings-headline-3-letter-spacing:-0.03125rem;--typography-headings-headline-4-font-size:1.5rem;--typography-headings-headline-4-superscript-font-size:.8399999737739563rem;--typography-headings-headline-4-superscript-leading:1.1200000047683716rem;--typography-headings-headline-4-leading:2rem;--typography-headings-headline-4-letter-spacing:-0.03125rem;--typography-headings-headline-5-font-size:1.25rem;--typography-headings-headline-5-superscript-font-size:.699999988079071rem;--typography-headings-headline-5-superscript-leading:.9800000190734863rem;--typography-headings-headline-5-leading:1.75rem;--typography-headings-headline-5-letter-spacing:-0.03125rem;--typography-headings-headline-6-font-size:1rem;--typography-headings-headline-6-superscript-font-size:.5600000023841858rem;--typography-headings-headline-6-superscript-leading:.8399999737739563rem;--typography-headings-headline-6-leading:1.5rem;--typography-headings-headline-6-letter-spacing:-0.03125rem;--typography-headings-overline-1-font-size:1rem;--typography-headings-overline-1-leading:1.375rem;--typography-headings-overline-1-letter-spacing:.25rem;--typography-headings-overline-2-font-size:.875rem;--typography-headings-overline-2-leading:1rem;--typography-headings-overline-2-letter-spacing:.25rem;--typography-headings-intro-intro-1-font-size:1.25rem;--typography-headings-intro-intro-1-leading:1.75rem;--typography-headings-intro-intro-1-letter-spacing:0rem;--typography-headings-intro-intro-2-font-size:1.125rem;--typography-headings-intro-intro-2-leading:1.5625rem;--typography-headings-intro-intro-2-letter-spacing:0rem;--typography-headings-intro-intro-3-font-size:1rem;--typography-headings-intro-intro-3-leading:1.5rem;--typography-headings-intro-intro-3-letter-spacing:0rem;--typography-headings-body-body-1-font-size:1rem;--typography-headings-body-body-1-leading:1.5rem;--typography-headings-body-body-1-letter-spacing:-0.015625rem;--typography-headings-body-body-2-font-size:.875rem;--typography-headings-body-body-2-leading:1.375rem;--typography-headings-body-body-2-letter-spacing:-0.015625rem;--typography-headi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-9col:343px;--grid-columns-10col:343px;--grid-columns-11col:343px;--grid-columns-12col:343px;--grid-inset-inset-1col:0;--grid-inset-inset-2col:0;--grid-inset-inset-3col:0;--grid-inset-inset-4col:0;--grid-inset-inset-5col:0;--grid-inset-inset-6col:0;--borders-weight-weight-0:0;--borders-weight-weight-1:1px;--borders-weight-weight-2:2px;--borders-weight-weight-3:3px;--borders-weight-weight-4:10px;--borders-cards-regular-stroke-top:2px;--borders-cards-regular-stroke-right:2px;--borders-cards-regular-stroke-bottom:2px;--borders-cards-regular-stroke-left:2px;--borders-cards-special-stroke-top:2px;--borders-cards-special-stroke-right:2px;--borders-cards-special-stroke-bottom:2px;--borders-cards-special-stroke-left:2px;--borders-media-audioplayer:4px;--borders-tabs-default-stroke:1px;--borders-tabs-default-bottom-stroke-selected:0;--borders-tabs-minimal-stroke-selected:2px;--borders-tabs-minimal-stroke-default:2px;--borders-accordion-divider-default:1px;--borders-accordion-divider-active:0;--borders-accordion-outline-default:0;--borders-accordion-outline-active:0;--borders-button-border-high:0;--borders-button-border-med:0;--borders-button-border-low:2px;--borders-navigation-dropdown-stroke-top:0;--borders-navigation-dropdown-stroke-bottom:0;--borders-navigation-dropdown-stroke-left:0;--borders-navigation-dropdown-stroke-right:0;--borders-navigation-menu-stroke-top:0;--borders-navigation-menu-stroke-bottom:0;--borders-navigation-utility-stroke-top:0;--borders-navigation-utility-stroke-bottom:0;--borders-navigation-footer-divider-top:0;--borders-navigation-in-page-nav-stroke-default:1px;--borders-navigation-in-page-nav-stroke-active:2px;--borders-navigation-in-page-nav-minimal-underline:3px;--borders-quiz-stroke-question:1px;--borders-quiz-stroke-indicator:1px;--borders-isi-stroke:0;--icon-size-icon-12:12px;--icon-size-icon-16:16px;--icon-size-icon-20:20px;--icon-size-icon-24:24px;--icon-size-icon-32:32px;--icon-size-icon-40:40px;--icon-size-icon-48:48px;--icon-size-icon-1col:76px;--icon-size-icon-under2col:105px;--icon-size-icon-2col:165px;--special-focus-frame:-4px;--special-accen-stroke-length:80px;--special-focus-weight:2px;--special-audioplayer-padding:10px}
@media(min-width:768px){:root{--spacing-components-desktop-0:0;--spacing-components-desktop-2:2px;--spacing-components-desktop-4:4px;--spacing-components-desktop-6:6px;--spacing-components-desktop-8:8px;--spacing-components-desktop-10:8px;--spacing-components-desktop-12:10px;--spacing-components-desktop-14:12px;--spacing-components-desktop-16:12px;--spacing-components-desktop-24:16px;--spacing-components-desktop-32:24px;--spacing-components-desktop-40:32px;--spacing-section-condensed:40px;--spacing-section-normal:48px;--spacing-section-spacious:56px;--spacing-document-condensed:64px;--spacing-document-normal:96px;--spacing-document-spacious:128px;--spacing-table-cell-top-and-bottom:12px;--spacing-table-cell-left-and-right:16px;--spacing-table-header-cell-default:56px;--spacing-table-header-cell-large:64px;--spacing-button-small-top-and-bottom:8px;--spacing-button-small-left-and-right:16px;--spacing-button-small-icon-only-left-and-right:8px;--spacing-button-regular-top-and-bottom:14px;--spacing-button-regular-left-and-right:28px;--spacing-button-regular-icon-only-left-and-right:14px;--spacing-button-large-top-and-bottom:16px;--spacing-button-large-left-and-right:40px;--spacing-button-large-icon-only-left-and-right:16px;--spacing-quiz-padding-top-bottom:12px;--spacing-quiz-padding-left-right:12px;--spacing-quiz-gap:12px;--spacing-menu-item-padding:16px;--spacing-menu-item-header-inside-padding-top:0;--spacing-menu-item-header-inside-padding-bottom:0;--spacing-forms-field-height:48px;--spacing-accordions-space-between:0;--spacing-tabs-space-between-horizontal:0;--spacing-tabs-space-between-vertical:16px;--spacing-tabs-tab-alt-padding:8px;--spacing-text-links-small:6px;--spacing-text-links-medium:11px;--spacing-text-links-large:14px;--typography-headings-jumbo-font-size:4.5rem;--typography-headings-jumbo-superscript-font-size:2.5199999809265137rem;--typography-headings-jumbo-superscript-leading:2.940000057220459rem;--typography-headings-jumbo-leading:5.25rem;--typography-headings-jumbo-letter-spacing:-0.1875rem;--typography-headings-headline-1-font-size:3rem;--typography-headings-headline-1-superscript-font-size:1.6799999475479126rem;--typography-headings-headline-1-superscript-leading:2.240000009536743rem;--typography-headings-headline-1-leading:4rem;--typography-headings-headline-1-letter-spacing:-0.0625rem;--typography-headings-headline-2-font-size:2.5rem;--typography-headings-headline-2-superscript-font-size:1.399999976158142rem;--typography-headings-headline-2-superscript-leading:1.9600000381469727rem;--typography-headings-headline-2-leading:3.5rem;--typography-headings-headline-2-letter-spacing:-0.0625rem;--typography-headings-headline-3-font-size:2rem;--typography-headings-headline-3-superscript-font-size:1.1200000047683716rem;--typography-headings-headline-3-superscript-leading:1.4700000286102295rem;--typography-headings-headline-3-leading:2.625rem;--typography-headings-headline-3-letter-spacing:-0.0625rem;--typography-headings-headline-4-font-size:1.75rem;--typography-headings-headline-4-superscript-font-size:.9800000190734863rem;--typography-headings-headline-4-superscript-leading:1.399999976158142rem;--typography-headings-headline-4-leading:2.5rem;--typography-headings-headline-4-letter-spacing:-0.03125rem;--typography-headings-headline-5-font-size:1.5rem;--typography-headings-headline-5-superscript-font-size:.8399999737739563rem;--typography-headings-headline-5-superscript-leading:1.2599999904632568rem;--typography-headings-headline-5-leading:2.25rem;--typography-headings-headline-5-letter-spacing:-0.03125rem;--typography-headings-headline-6-font-size:1.25rem;--typography-headings-headline-6-superscript-font-size:.699999988079071rem;--typography-headings-headline-6-superscript-leading:.9800000190734863rem;--typography-headings-headline-6-leading:1.75rem;--typography-headings-headline-6-letter-spacing:-0.03125rem;--typography-headings-overline-1-font-size:1rem;--typography-headings-overline-1-leading:1rem;--typography-headings-overline-1-letter-spacing:.25rem;--typography-headings-overline-2-font-size:.875rem;--typography-headings-overline-2-leading:.875rem;--typography-headings-overline-2-letter-spacing:.25rem;--typography-headings-intro-intro-1-font-size:1.25rem;--typography-headings-intro-intro-1-leading:1.75rem;--typography-headings-intro-intro-1-letter-spacing:-0.03125rem;--typography-headings-intro-intro-2-font-size:1.125rem;--typography-headings-intro-intro-2-leading:1.5625rem;--typography-headings-intro-intro-2-letter-spacing:-0.03125rem;--typography-headings-intro-intro-3-font-size:1rem;--typography-headings-intro-intro-3-leading:1.5rem;--typography-headings-intro-intro-3-letter-spacing:-0.03125rem;--typography-headings-body-body-1-font-size:1rem;--typography-headings-body-body-1-leading:1.5rem;--typography-headings-body-body-1-letter-spacing:-0.015625rem;--typography-headings-body-body-2-font-size:.875rem;--typography-headings-body-body-2-leading:1.375rem;--typography-headings-body-body-2-letter-spacing:-0.015625rem;--typography-headings-body-body-3-font-size:.75rem;--typography-headings-body-body-3-leading:1.125rem;--typography-headings-body-body-3-letter-spacing:-0.015625rem;--typography-headings-body-inline-1-font-size:1.25rem;--typography-headings-body-inline-1-leading:1.75rem;--typography-headings-body-inline-1-letter-spacing:0rem;--typography-headings-body-inline-2-font-size:1rem;--typography-headings-body-inline-2-leading:1.5rem;--typography-headings-body-inline-2-letter-spacing:0rem;--typography-headings-body-inline-3-font-size:.875rem;--typography-headings-body-inline-3-leading:1.375rem;--typography-headings-body-inline-3-letter-spacing:0rem;--typography-headings-cta-large-font-size:1.25rem;--typography-headings-cta-large-leading:1.75rem;--typography-headings-cta-large-letter-spacing:0rem;--typography-headings-cta-medium-font-size:1rem;--typography-headings-cta-medium-leading:1.5rem;--typography-headings-cta-medium-letter-spacing:0rem;--typography-headings-cta-small-font-size:.75rem;--typography-headings-cta-small-leading:1.125rem;--typography-headings-cta-small-letter-spacing:0rem;--typography-navigation-level-1-font-size:1rem;--typography-navigation-level-1-leading:1.5rem;--typography-navigation-level-1-letter-spacing:0rem;--typography-navigation-level-2-font-size:.875rem;--typography-navigation-level-2-leading:1.375rem;--typography-navigation-level-2-letter-spacing:0rem;--typography-navigation-utility-font-size:.875rem;--typography-navigation-utility-leading:1.375rem;--typography-navigation-utility-letter-spacing:0rem;--typography-navigation-footer-font-size:.875rem;--typography-navigation-footer-leading:1.375rem;--typography-navigation-footer-letter-spacing:0rem;--typography-data-1-font-size:6rem;--typography-data-1-superscript-font-size:3.359999895095825rem;--typography-data-1-leading:7.1875rem;--typography-data-1-superscript-leading:4.025000095367432rem;--typography-data-1-letter-spacing:0rem;--typography-data-2-font-size:5rem;--typography-data-2-superscript-font-size:2.799999952316284rem;--typography-data-2-leading:5.5rem;--typography-data-2-superscript-leading:3.0799999237060547rem;--typography-data-2-letter-spacing:0rem;--typography-data-3-font-size:3.5rem;--typography-data-3-superscript-font-size:1.9600000381469727rem;--typography-data-3-leading:4.5rem;--typography-data-3-superscript-leading:2.5199999809265137rem;--typography-data-3-letter-spacing:0rem;--typography-data-4-font-size:2.5rem;--typography-data-4-superscript-font-size:1.399999976158142rem;--typography-data-4-leading:3.5rem;--typography-data-4-superscript-leading:1.9600000381469727rem;--typography-data-4-letter-spacing:-0.0625rem;--typography-data-5-font-size:1.75rem;--typography-data-5-superscript-font-size:.9800000190734863rem;--typography-data-5-leading:2.5rem;--typography-data-5-superscript-leading:1.399999976158142rem;--typography-data-5-letter-spacing:-0.0625rem;--spacing-primitives-spacing-0:0;--spacing-primitives-spacing-2:2px;--spacing-primitives-spacing-4:4px;--spacing-primitives-spacing-6:6px;--spacing-primitives-spacing-8:8px;--spacing-primitives-spacing-10:10px;--spacing-primitives-spacing-12:12px;--spacing-primitives-spacing-14:14px;--spacing-primitives-spacing-16:16px;--spacing-primitives-spacing-18:18px;--spacing-primitives-spacing-24:24px;--spacing-primitives-spacing-28:28px;--spacing-primitives-spacing-32:32px;--spacing-primitives-spacing-40:40px;--spacing-primitives-spacing-48:48px;--spacing-primitives-spacing-56:56px;--spacing-primitives-spacing-60:60px;--spacing-primitives-spacing-64:64px;--spacing-primitives-spacing-72:72px;--spacing-primitives-spacing-80:80px;--spacing-primitives-spacing-96:96px;--spacing-primitives-spacing-120:120px;--spacing-primitives-spacing-128:128px;--spacing-primitives-spacing-144:144px;--spacing-primitives-spacing-160:160px;--grid-foundations-display-width:768px;--grid-foundations-outer-margin:42px;--grid-foundations-gutter:18px;--grid-foundations-container-width:684px;--grid-components-divider-padding:2px;--grid-components-divider-negative-margin:-18px;--grid-components-logo-negative-margin:-6px;--grid-components-carousel-negative-margin:-16px;--grid-components-comparison-vertical-negative-offset:-39px;--grid-components-comparison-vertical-negative-gap:-21px;--grid-components-comparison-horizontal-negative-offset:-54px;--grid-components-section-horizontal-negative-margin:-105px;--grid-components-section-vertical-negative-margin:-72px;--grid-components-comparison-horizontal-negative-gap:-22px;--grid-components-sticky-side-cta-max-width:285px;--grid-components-card-top-overlap-padding:114px;--grid-components-timestamp-negative-padding:-24px;--grid-components-header-logo-margin:0;--grid-components-isi-width-closed:768px;--grid-components-isi-width-open:768px;--grid-components-carousel-controls-lr-padding:10px;--grid-columns-1col:99px;--grid-columns-2col:216px;--grid-columns-3col:333px;--grid-columns-4col:333px;--grid-columns-5col:333px;--grid-columns-6col:684px;--grid-columns-7col:684px;--grid-columns-8col:684px;--grid-columns-9col:684px;--grid-columns-10col:684px;--grid-columns-11col:684px;--grid-columns-12col:684px;--grid-inset-inset-1col:0;--grid-inset-inset-2col:0;--grid-inset-inset-3col:0;--grid-inset-inset-4col:0;--grid-inset-inset-5col:0;--grid-inset-inset-6col:0;--borders-weight-weight-0:0;--borders-weight-weight-1:1px;--borders-weight-weight-2:2px;--borders-weight-weight-3:3px;--borders-weight-weight-4:10px;--borders-cards-regular-stroke-top:2px;--borders-cards-regular-stroke-right:2px;--borders-cards-regular-stroke-bottom:2px;--borders-cards-regular-stroke-left:2px;--borders-cards-special-stroke-top:2px;--borders-cards-special-stroke-right:2px;--borders-cards-special-stroke-bottom:2px;--borders-cards-special-stroke-left:2px;--borders-media-audioplayer:4px;--borders-tabs-default-stroke:1px;--borders-tabs-default-bottom-stroke-selected:0;--borders-tabs-minimal-stroke-selected:2px;--borders-tabs-minimal-stroke-default:1px;--borders-accordion-divider-default:1px;--borders-accordion-divider-active:0;--borders-accordion-outline-default:0;--borders-accordion-outline-active:0;--borders-button-border-high:0;--borders-button-border-med:0;--borders-button-border-low:2px;--borders-navigation-dropdown-stroke-top:0;--borders-navigation-dropdown-stroke-bottom:0;--borders-navigation-dropdown-stroke-left:0;--borders-navigation-dropdown-stroke-right:0;--borders-navigation-menu-stroke-top:0;--borders-navigation-menu-stroke-bottom:0;--borders-navigation-utility-stroke-top:0;--borders-navigation-utility-stroke-bottom:0;--borders-navigation-footer-divider-top:0;--borders-navigation-in-page-nav-stroke-default:1px;--borders-navigation-in-page-nav-stroke-active:2px;--borders-navigation-in-page-nav-minimal-underline:3px;--borders-quiz-stroke-question:1px;--borders-quiz-stroke-indicator:1px;--borders-isi-stroke:0;--icon-size-icon-12:12px;--icon-size-icon-16:16px;--icon-size-icon-20:20px;--icon-size-icon-24:24px;--icon-size-icon-32:32px;--icon-size-icon-40:40px;--icon-size-icon-48:48px;--icon-size-icon-1col:99px;--icon-size-icon-under2col:105px;--icon-size-icon-2col:216px;--special-focus-frame:-4px;--special-accen-stroke-length:120px;--special-focus-weight:2px;--special-audioplayer-padding:10px}
}
@media(min-width:992px){:root{--spacing-components-desktop-0:0;--spacing-components-desktop-2:2px;--spacing-components-desktop-4:4px;--spacing-components-desktop-6:6px;--spacing-components-desktop-8:8px;--spacing-components-desktop-10:10px;--spacing-components-desktop-12:12px;--spacing-components-desktop-14:14px;--spacing-components-desktop-16:16px;--spacing-components-desktop-24:24px;--spacing-components-desktop-32:32px;--spacing-components-desktop-40:40px;--spacing-section-condensed:48px;--spacing-section-normal:56px;--spacing-section-spacious:64px;--spacing-document-condensed:80px;--spacing-document-normal:120px;--spacing-document-spacious:160px;--spacing-table-cell-top-and-bottom:16px;--spacing-table-cell-left-and-right:18px;--spacing-table-header-cell-default:64px;--spacing-table-header-cell-large:96px;--spacing-button-small-top-and-bottom:10px;--spacing-button-small-left-and-right:18px;--spacing-button-small-icon-only-left-and-right:10px;--spacing-button-regular-top-and-bottom:14px;--spacing-button-regular-left-and-right:28px;--spacing-button-regular-icon-only-left-and-right:14px;--spacing-button-large-top-and-bottom:16px;--spacing-button-large-left-and-right:40px;--spacing-button-large-icon-only-left-and-right:16px;--spacing-quiz-padding-top-bottom:12px;--spacing-quiz-padding-left-right:16px;--spacing-quiz-gap:16px;--spacing-menu-item-padding:24px;--spacing-menu-item-header-inside-padding-top:0;--spacing-menu-item-header-inside-padding-bottom:0;--spacing-forms-field-height:48px;--spacing-accordions-space-between:0;--spacing-tabs-space-between-horizontal:0;--spacing-tabs-space-between-vertical:24px;--spacing-tabs-tab-alt-padding:8px;--spacing-text-links-small:7px;--spacing-text-links-medium:11px;--spacing-text-links-large:14px;--typography-headings-jumbo-font-size:4.5rem;--typography-headings-jumbo-superscript-font-size:2.5199999809265137rem;--typography-headings-jumbo-superscript-leading:2.940000057220459rem;--typography-headings-jumbo-leading:5.25rem;--typography-headings-jumbo-letter-spacing:-0.1875rem;--typography-headings-headline-1-font-size:3.5rem;--typography-headings-headline-1-superscript-font-size:1.9600000381469727rem;--typography-headings-headline-1-superscript-leading:2.5199999809265137rem;--typography-headings-headline-1-leading:4.5rem;--typography-headings-headline-1-letter-spacing:0rem;--typography-headings-headline-2-font-size:3rem;--typography-headings-headline-2-superscript-font-size:1.6799999475479126rem;--typography-headings-headline-2-superscript-leading:2.240000009536743rem;--typography-headings-headline-2-leading:4rem;--typography-headings-headline-2-letter-spacing:0rem;--typography-headings-headline-3-font-size:2.5rem;--typography-headings-headline-3-superscript-font-size:1.399999976158142rem;--typography-headings-headline-3-superscript-leading:1.9600000381469727rem;--typography-headings-headline-3-leading:3.5rem;--typography-headings-headline-3-letter-spacing:0rem;--typography-headings-headline-4-font-size:1.75rem;--typography-headings-headline-4-superscript-font-size:.9800000190734863rem;--typography-headings-headline-4-superscript-leading:1.399999976158142rem;--typography-headings-headline-4-leading:2.5rem;--typography-headings-headline-4-letter-spacing:0rem;--typography-headings-headline-5-font-size:1.5rem;--typography-headings-headline-5-superscript-font-size:.8399999737739563rem;--typography-headings-headline-5-superscript-leading:1.1200000047683716rem;--typography-headings-headline-5-leading:2rem;--typography-headings-headline-5-letter-spacing:0rem;--typography-headings-headline-6-font-size:1.25rem;--typography-headings-headline-6-superscript-font-size:.699999988079071rem;--typography-headings-headline-6-superscript-leading:.9800000190734863rem;--typography-headings-headline-6-leading:1.75rem;--typography-headings-headline-6-letter-spacing:0rem;--typography-headings-overline-1-font-size:1rem;--typography-headings-overline-1-leading:1.375rem;--typography-headings-overline-1-letter-spacing:.25rem;--typography-headings-overline-2-font-size:.875rem;--typography-headings-overline-2-leading:1rem;--typography-headings-overline-2-letter-spacing:.25rem;--typography-headings-intro-intro-1-font-size:1.75rem;--typography-headings-intro-intro-1-leading:2.5rem;--typography-headings-intro-intro-1-letter-spacing:0rem;--typography-headings-intro-intro-2-font-size:1.5rem;--typography-headings-intro-intro-2-leading:2.25rem;--typography-headings-intro-intro-2-letter-spacing:0rem;--typography-headings-intro-intro-3-font-size:1.25rem;--typography-headings-intro-intro-3-leading:1.75rem;--typography-headings-intro-intro-3-letter-spacing:0rem;--typography-headings-body-body-1-font-size:1rem;--typography-headings-body-body-1-leading:1.5rem;--typography-headings-body-body-1-letter-spacing:0rem;--typography-headings-body-body-2-font-size:.875rem;--typography-headings-body-body-2-leading:1.375rem;--typography-headings-body-body-2-letter-spacing:0rem;--typography-headings-body-body-3-font-size:.75r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0col:1020px;--grid-columns-11col:1125px;--grid-columns-12col:1230px;--grid-inset-inset-1col:105px;--grid-inset-inset-2col:210px;--grid-inset-inset-3col:315px;--grid-inset-inset-4col:420px;--grid-inset-inset-5col:525px;--grid-inset-inset-6col:630px;--borders-weight-weight-0:0;--borders-weight-weight-1:1px;--borders-weight-weight-2:2px;--borders-weight-weight-3:3px;--borders-weight-weight-4:10px;--borders-cards-regular-stroke-top:2px;--borders-cards-regular-stroke-right:2px;--borders-cards-regular-stroke-bottom:2px;--borders-cards-regular-stroke-left:2px;--borders-cards-special-stroke-top:2px;--borders-cards-special-stroke-right:2px;--borders-cards-special-stroke-bottom:2px;--borders-cards-special-stroke-left:2px;--borders-media-audioplayer:4px;--borders-tabs-default-stroke:1px;--borders-tabs-default-bottom-stroke-selected:0;--borders-tabs-minimal-stroke-selected:2px;--borders-tabs-minimal-stroke-default:1px;--borders-accordion-divider-default:1px;--borders-accordion-divider-active:0;--borders-accordion-outline-default:0;--borders-accordion-outline-active:0;--borders-button-border-high:0;--borders-button-border-med:0;--borders-button-border-low:2px;--borders-navigation-dropdown-stroke-top:0;--borders-navigation-dropdown-stroke-bottom:0;--borders-navigation-dropdown-stroke-left:0;--borders-navigation-dropdown-stroke-right:0;--borders-navigation-menu-stroke-top:0;--borders-navigation-menu-stroke-bottom:0;--borders-navigation-utility-stroke-top:0;--borders-navigation-utility-stroke-bottom:0;--borders-navigation-footer-divider-top:0;--borders-navigation-in-page-nav-stroke-default:1px;--borders-navigation-in-page-nav-stroke-active:2px;--borders-navigation-in-page-nav-minimal-underline:3px;--borders-quiz-stroke-question:1px;--borders-quiz-stroke-indicator:1px;--borders-isi-stroke:0;--icon-size-icon-12:12px;--icon-size-icon-16:16px;--icon-size-icon-20:20px;--icon-size-icon-24:24px;--icon-size-icon-32:32px;--icon-size-icon-40:40px;--icon-size-icon-48:48px;--icon-size-icon-1col:75px;--icon-size-icon-under2col:105px;--icon-size-icon-2col:180px;--special-focus-frame:-4px;--special-accen-stroke-length:180px;--special-focus-weight:2px;--special-audioplayer-padding:16px}
}
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@media(min-width:768px){:root{--spacing-accordion-space-between:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-accordion-space-between);--spacing-forms-height:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-forms-height);--spacing-header-inside-padding-bottom:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-header-inside-padding-bottom);--spacing-header-inside-padding-top:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-header-inside-padding-top);--spacing-header-logo-margin:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-header-logo-margin);--spacing-menu-item-padding:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-menu-item-padding);--spacing-quiz-gap:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-quiz-gap);--spacing-quiz-padding-left-right:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-quiz-padding-left-right);--spacing-quiz-padding-top-bottom:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-quiz-padding-top-bottom);--spacing-special-accent-stroke-lenght:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-special-accent-stroke-lenght);--spacing-special-audioplayer-padding:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-special-audioplayer-padding);--spacing-special-carousel-controls-lr-padding:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-special-carousel-controls-lr-padding);--spacing-special-isi-width-closed:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-special-isi-width-closed);--spacing-special-isi-width-open:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-special-isi-width-open);--spacing-tabs-space-between-horizontal:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-tabs-space-between-horizontal);--spacing-tabs-space-between-vertical:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-tabs-space-between-vertical);--spacing-tabs-tab-alt-padding:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-tabs-tab-alt-padding);--spacing-tabs-tab-alt-space-between:var(--brand-primitives-channel-sizing-web-tablet-component-spacing-tabs-tab-alt-space-between)}
}
@media(min-width:992px){:root{--spacing-accordion-space-between:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-accordion-space-between);--spacing-forms-height:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-forms-height);--spacing-header-inside-padding-bottom:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-header-inside-padding-bottom);--spacing-header-inside-padding-top:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-header-inside-padding-top);--spacing-header-logo-margin:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-header-logo-margin);--spacing-menu-item-padding:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-menu-item-padding);--spacing-quiz-gap:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-quiz-gap);--spacing-quiz-padding-left-right:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-quiz-padding-left-right);--spacing-quiz-padding-top-bottom:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-quiz-padding-top-bottom);--spacing-special-accent-stroke-length:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-special-accent-stroke-length);--spacing-special-audioplayer-padding:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-special-audioplayer-padding);--spacing-special-carousel-controls-lr-padding:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-special-carousel-controls-lr-padding);--spacing-special-isi-width-closed:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-special-isi-width-closed);--spacing-special-isi-width-open:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-special-isi-width-open);--spacing-tabs-space-between-horizontal:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-tabs-space-between-horizontal);--spacing-tabs-space-between-vertical:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-tabs-space-between-vertical);--spacing-tabs-tab-alt-padding:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-tabs-tab-alt-padding);--spacing-tabs-tab-alt-space-between:var(--brand-primitives-channel-sizing-web-desktop-component-spacing-tabs-tab-alt-space-between)}
}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:100;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-100.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-100.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:100;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-100italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-100italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:200;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-200.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-200.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:200;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-200italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-200italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:300;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-300.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-300.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:300;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-300italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-300italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:400;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-regular.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-regular.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:400;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:500;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-500.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-500.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:500;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-500italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-500italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:600;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-600.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-600.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:600;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-600italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-600italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:700;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-700.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-700.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:700;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-700italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-700italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:800;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-800.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-800.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:800;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-800italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-800italic.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:normal;font-weight:900;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-900.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-900.woff") format("woff")}
@font-face{font-family:"Montserrat";font-style:italic;font-weight:900;font-display:swap;src:url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-900italic.woff2") format("woff2"),url("https://fonts.amgen.com/s/montserrat/v25/montserrat-v25-vietnamese_latin-ext_latin_cyrillic-ext_cyrillic-900italic.woff") format("woff")}
@layer core,brand;@layer brand{.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button{background-color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-background-default);border-radius:var(--brand-primitives-corner-radius-forms-radius-checkboxes-focus)}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button .amg-accordion__title-content{color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-icon-default);flex-direction:row-reverse;justify-content:flex-end}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button .amg-accordion__title-text{color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-label-default)}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button .amg-accordion__title [slot=title]{color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-label-default);font-size:var(--typography-headings-headline-4-font-size)}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button:hover{background-color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-background-active);border-radius:var(--brand-primitives-corner-radius-forms-radius-formfields)}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button:hover .amg-accordion__title [slot=title]{color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-label-active)}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button:hover .chevron{color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-icon-active)}
.amg-accordion:not(amg-tab .amg-accordion){border-radius:var(--brand-primitives-corner-radius-forms-radius-checkboxes-focus);border:var(--brand-primitives-borders-accordion-outline-active) solid var(--component-theme-light-surface-interactive-accordion-medium-prominence-outline-active)}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button .chevron{color:var(--component-theme-light-surface-interactive-accordion-medium-prominence-icon-default)}
.amg-accordion.is-open>.amg-accordion__panel>.amg-accordion__content{padding:var(--spacing-primitives-spacing-12) var(--spacing-primitives-spacing-32)}
.lumakras-dosing-accordion .amg-accordion-group{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16);gap:var(--spacing-primitives-spacing-32)}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content-block--1 .cmp-text{padding:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-16);display:flex;align-items:center;gap:var(--spacing-primitives-spacing-12);text-align:center}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content{align-items:center;padding-bottom:var(--spacing-primitives-spacing-10)}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content .amg-bg-section-2{border-radius:var(--brand-primitives-corner-radius-base-radius-base);min-height:11.5625rem;display:flex;align-items:center;justify-content:center}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content-block--2{width:1.375rem}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content-block--3 .cmp-text{padding:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-16)}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content-block--3 .accordion-list-block ul{list-style:none !important;padding-left:var(--spacing-primitives-spacing-16) !important}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content-block--3 .accordion-list-block ul li{padding-bottom:var(--spacing-primitives-spacing-12)}
.laboratory-abnormalities .amg-accordion-group{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.additional-safety-consideration .amg-accordion-group{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.amg-accordion__header-button[aria-expanded=true] .chevron{transform:none}
@media(max-width:767px){.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content{gap:var(--spacing-primitives-spacing-16)}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content-block--2{margin-inline:auto;width:3.75rem}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content-block--1 .cmp-text{padding:var(--spacing-primitives-spacing-16);flex-direction:column}
.lumakras-dosing-accordion .amg-accordion-group .amg-section-with-slots__content .amg-bg-section-2{min-height:auto}
.amg-accordion.is-open>.amg-accordion__panel>.amg-accordion__content{padding:var(--spacing-primitives-spacing-24)}
.amg-accordion:not(amg-tab .amg-accordion) .amg-accordion__header-button{padding:var(--spacing-primitives-spacing-10) var(--spacing-primitives-spacing-16)}
.amg-accordion.is-open>.amg-accordion__panel>.amg-accordion__content{padding:var(--spacing-primitives-spacing-16)}
}
.amg-back-to-top{flex-direction:row-reverse;width:max-content;gap:var(--spacing-primitives-spacing-24);background-color:var(--component-theme-light-surface-interactive-base-high-prominence-text-icon-interactive);border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-primary-dark-base);box-shadow:none;padding-inline:var(--spacing-primitives-spacing-16)}
.amg-back-to-top:hover{background-color:var(--brand-primitives-color-primary-dark-base)}
.amg-back-to-top:hover .back-to-top-text{color:var(--component-theme-light-surface-interactive-base-high-prominence-text-icon-interactive)}
.amg-back-to-top .back-to-top-text{width:max-content;color:var(--brand-primitives-color-primary-dark-base)}
.amg-back-to-top amg-icon iconify-icon{color:var(--brand-primitives-color-secondary-light-tint-2)}
.back-to-top-v2{width:100% !important;bottom:16.5625rem !important;max-width:fit-content}
amg-back-to-top{position:relative;bottom:unset;margin-left:auto !important;right:0;margin-bottom:-1.5rem}
@media(max-width:767px){.back-to-top-v2{position:static !important;margin:0 auto;max-width:unset}
amg-back-to-top{margin-inline:auto;width:100%;justify-content:center;margin-top:var(--spacing-primitives-spacing-24);right:unset;margin-bottom:0}
}
:root{--heading-font-family:var(--brand-primitives-typography-styles-font-family-headings);--body-font-family:var(--brand-primitives-typography-styles-font-family-body);--f-h1-56:normal 800 var(--typography-headings-headline-1-font-size)/var(--typography-headings-headline-1-leading) var(--heading-font-family);--f-h2-48:normal 800 var(--typography-headings-headline-2-font-size)/var(--typography-headings-headline-2-leading) var(--heading-font-family);--f-h3-40:normal 800 var(--typography-headings-headline-3-font-size)/var(--typography-headings-headline-3-leading) var(--heading-font-family);--f-h4-28:normal 800 var(--typography-headings-headline-4-font-size)/var(--typography-headings-headline-4-leading) var(--heading-font-family);--f-h5-24:normal 800 var(--typography-headings-headline-5-font-size)/var(--typography-headings-headline-5-leading) var(--heading-font-family);--f-h6-20:normal 800 var(--typography-headings-headline-6-font-size)/var(--typography-headings-headline-6-leading) var(--heading-font-family);--f-p-16:normal 400 var(--typography-headings-body-body-1-font-size)/var(--brand-primitives-channel-sizing-web-tablet-body-1-leading) var(--body-font-family);--f-p-12:normal 400 var(--brand-primitives-channel-sizing-web-desktop-body-3-font-size)/var(--typography-headings-body-body-3-leading) var(--body-font-family)}
.container-width{max-width:76.875rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.amg-references__content{font:var(--f-p-12) !important}
.text-shadow{text-shadow:var(--text-shadow)}
p,h1,h2,h3,h4,h5,h6{text-wrap:initial}
.pb-40{padding-bottom:2.5rem}
.amg-font-bold sup{font-weight:700}
.pt-40{padding-top:2.5rem}
.pb-32{padding-bottom:2rem}
.inner-page-width{max-width:63.75rem;margin:0 auto;padding:0 var(--spacing-primitives-spacing-16)}
.global-list-icon ul{list-style:none;padding-left:16px}
.global-list-icon ul li{position:relative}
.global-list-icon ul li:before{content:"";background-image:url(data:image/svg+xml;base64,PHN2ZyB3aWR0aD0iMTAiIGhlaWdodD0iMTAiIHZpZXdCb3g9IjAgMCAxMCAxMCIgZmlsbD0ibm9uZSIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj4KPHBhdGggZD0iTTMuMzI3NDggNy4yNjIxOUM0LjU3Njc0IDguMTg2ODEgNi4zMzkwMiA3LjkyMzYzIDcuMjYzNjQgNi42NzQzN0M4LjE4ODI2IDUuNDI1MTEgNy45MjUwOSAzLjY2MjgzIDYuNjc1ODMgMi43MzgyMUw3LjEyODMxIDIuMTI2ODZDOC43MTUyMSAzLjMwMTM4IDkuMDQ5NTEgNS41Mzk5NSA3Ljg3NDk5IDcuMTI2ODVDNi43MDA0NyA4LjcxMzc1IDQuNDYxOSA5LjA0ODA1IDIuODc1IDcuODczNTRMMy4zMjc0OCA3LjI2MjE5WiIgZmlsbD0iI0U3MjQ0NCIvPgo8cGF0aCBkPSJNNi42NzY0MyAyLjczODA2QzUuNDI3MTYgMS44MTM0NCAzLjY2NDg4IDIuMDc2NjEgMi43NDAyNiAzLjMyNTg3QzEuODE1NjQgNC41NzUxMyAyLjA3ODgyIDYuMzM3NDEgMy4zMjgwOCA3LjI2MjA0TDIuODc1NiA3Ljg3MzM4QzEuMjg4NyA2LjY5ODg3IDAuOTU0Mzk2IDQuNDYwMjkgMi4xMjg5MSAyLjg3MzM5QzMuMzAzNDMgMS4yODY0OSA1LjU0MjAxIDAuOTUyMTkgNy4xMjg5MSAyLjEyNjcxTDYuNjc2NDMgMi43MzgwNloiIGZpbGw9IiMxRTU2N0UiLz4KPC9zdmc+);background-color:transparent;background-repeat:no-repeat;background-size:contain;display:block;top:.3125rem;position:absolute;left:-1.375rem;width:.75rem;height:.75rem}
.global-common-footnote{padding-block:var(--spacing-primitives-spacing-32) 0}
.global-common-footnote p{text-indent:-0.375rem;padding-left:var(--spacing-primitives-spacing-6);padding-bottom:var(--spacing-primitives-spacing-8)}
.global-common-footnote p:last-child{text-indent:0}
.discover-luma .container:first-child{background:var(--section-header-background-color)}
.discover-luma .container:nth-child(2){position:relative}
.audio-container{position:absolute;bottom:1.5625rem;left:42%}
.discover-luma{position:relative}
.discover-luma .amg-brightcove-video{max-width:62%}
.discover-luma .amg-brightcove-video .amg-brightcove-video__audio-title{overflow:unset !important;text-overflow:unset !important;white-space:unset !important}
.discover-luma .amg-brightcove-video .amg-brightcove-video__audio-volume-btn iconify-icon{font-size:2rem}
.discover-luma .amg-brightcove-video__audio-player:hover .amg-brightcove-video__audio-title{font-weight:700 !important}
@media(max-width:767px){.discover-luma .container:nth-child(2){position:static}
.audio-container{position:static;padding-left:var(--spacing-primitives-spacing-16)}
amg-brightcove-video[audio-player] .amg-brightcove-video__audio-player{padding:0 !important}
.discover-luma .amg-brightcove-video{max-width:68%;margin-bottom:var(--spacing-primitives-spacing-24)}
}
.amg-card--horizontal{box-shadow:none;background:0}
.amg-card--horizontal .amg-card__media{max-width:20%;padding:0}
.home-nsclc-bg .amg-card__content{padding-block:var(--spacing-primitives-spacing-56);padding-inline:var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-0)}
.real-word-card{gap:var(--spacing-primitives-spacing-16)}
.real-word-card .amg-card__content{padding:0}
.real-word-card .amg-content-icon{justify-content:flex-start;width:4.6875rem;height:auto}
.real-word-card .amg-content-icon .amg-content-icon__icon{justify-content:flex-start}
.real-word-card .amg-content-icon .amg-card__content{padding:0;gap:0}
.real-word-card .amg-card__body ul{padding-left:var(--spacing-primitives-spacing-40)}
.real-word-card .amg-card__body ul li{position:relative}
.real-word-card .amg-card__body ul li:before{content:"";background-image:url(data:image/svg+xml;base64,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);background-color:transparent;background-repeat:no-repeat;background-size:contain;display:block;top:.5rem;position:absolute;left:-1.375rem;width:.75rem;height:.75rem}
.multi-card{margin-block:var(--spacing-primitives-spacing-24)}
.card-foot-note{padding-block:var(--spacing-primitives-spacing-18)}
.card-foot-note p{padding-left:var(--spacing-primitives-spacing-8);text-indent:-0.5rem}
.download-resource-container .amg-section-with-slots .amg-section-with-slots__content{gap:var(--spacing-primitives-spacing-60)}
.download-resource-container .amg-section-with-slots{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.download-resource-container .card-top-text{text-align:center}
.download-resource-container .amg-card__content{align-items:center;gap:var(--spacing-primitives-spacing-16)}
.download-resource-container .amg-card__content a{text-align:center;line-height:normal;text-decoration:none}
.download-resource-container .amg-section-with-slots [slot=content-block-02] .amg-card__media{padding-top:var(--spacing-primitives-spacing-48)}
.download-resource-container .amg-section-with-slots [slot=content-block-02] .amg-card__content{padding-top:var(--spacing-primitives-spacing-48)}
.download-resource-container .amg-section-with-slots .amg-card__media{padding-inline:0;width:26.875rem;margin-inline:auto}
.download-resource-container .amg-section-with-slots .amg-card__content{padding-inline:0}
.download-resource-container .amg-section-with-slots .amg-card__actions a{font-size:var(--brand-primitives-channel-sizing-web-desktop-cta-large-font-size);line-height:var(--brand-primitives-channel-sizing-web-desktop-cta-large-leading)}
.download-resource-container .amg-section-with-slots .amg-card__actions a iconify-icon{font-size:var(--brand-primitives-channel-sizing-web-desktop-cta-large-font-size) !important;color:var(--brand-primitives-color-section-section-bg-dark-1)}
#discover-support{padding-inline:0}
.call-your-lab .responsivegrid{max-width:63.75rem !important;padding-inline:var(--spacing-primitives-spacing-16)}
.observation-sugtn .amg-section-with-slots{max-width:63.75rem;margin:var(--spacing-primitives-spacing-32) auto 0;padding-inline:var(--spacing-primitives-spacing-16)}
.observation-sugtn .amg-section-with-slots .obs-sug-text{text-align:center}
.observation-sugtn .amg-section-with-slots .obs-sug-text h5{margin-bottom:var(--spacing-primitives-spacing-18)}
.once-daily-card{padding:var(--spacing-primitives-spacing-0);border-radius:7.8125rem var(--brand-primitives-corner-radius-cards-radius-cards-ur) var(--brand-primitives-corner-radius-cards-radius-cards-lr) 7.8125rem;background:var(--background-gradient-discover-page) !important;margin-block:var(--spacing-primitives-spacing-24)}
.once-daily-card .amg-content-icon{width:9.6875rem;height:9.375rem}
.code-break-single{padding-block:var(--spacing-primitives-spacing-24)}
.first-sec-last-card .amg-section-with-slots__content{max-width:63.75rem;margin:0 auto var(--spacing-primitives-spacing-40);padding-inline:var(--spacing-primitives-spacing-16);gap:var(--spacing-primitives-spacing-48);width:100%}
.first-sec-last-card .amg-section-with-slots__content .amg-card{border-radius:var(--brand-primitives-corner-radius-cards-radius-cards-ul) var(--brand-primitives-corner-radius-cards-radius-cards-ur) var(--brand-primitives-corner-radius-cards-radius-cards-lr) var(--brand-primitives-corner-radius-cards-radius-cards-ll);border:var(--borders-weight-weight-1) solid var(--component-theme-light-surface-interactive-base-outline-default);background:var(--gradient-light-bg-gradient-with-opacity);box-shadow:0 .25rem 1rem 0 var(--brand-primitives-color-neutral-dark-alpha-16);padding:var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-0);min-height:20.625rem;max-width:100%;width:100%}
.first-sec-last-card .amg-section-with-slots__content .amg-card .amg-card__media{padding:var(--spacing-primitives-spacing-0);margin:0 auto}
.first-sec-last-card .amg-section-with-slots__content .amg-card .amg-card__content{padding:var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-24)}
.support-resource-card{justify-content:flex-start;align-items:center;padding-block:var(--spacing-primitives-spacing-24);padding-inline:0}
.support-resource-card .amg-card__media{background:transparent;border-radius:0;max-width:fit-content;width:100%}
.support-resource-card .amg-card__media .amg-card__media--image{width:6.5625rem;height:6.5625rem}
.support-resource-card .amg-card__content{width:100%;padding-block:0}
.support-resource-card .amg-card__content .amg-text-subtle{color:var(--support-text-reveresd)}
.support-resource-card .amg-card__content .amg-card__body p:not(:first-child){text-indent:-0.3125rem;padding-left:var(--spacing-primitives-spacing-8)}
.oral-kras-bg-grad{background:var(--gradient-primary-bg-gradient-with-opacity);border-radius:var(--brand-primitives-corner-radius-base-radius-base);padding:var(--spacing-primitives-spacing-40);text-align:center;margin-block:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-40)}
.confirm-dose{max-width:56.875rem;margin-bottom:var(--spacing-primitives-spacing-32)}
.confirm-dose ul{padding-left:var(--spacing-primitives-spacing-18)}
.orphan-cards .amg-card--horizontal{gap:var(--spacing-primitives-spacing-16)}
.orphan-cards .amg-card--horizontal .amg-content-icon{width:7.8125rem;height:7.8125rem}
.orphan-cards .amg-card--horizontal .cards .button a{width:17.5rem}
.orphan-cards .amg-card--horizontal .amg-card__media{height:fit-content}
.orphan-cards .amg-card--horizontal .amg-card__content{padding-block:0}
.orphan-cards .amg-card--horizontal .amg-card__content h5{padding-bottom:var(--spacing-primitives-spacing-8)}
.orphan-cards .amg-card--horizontal .amg-card__content h5 + h5{padding-block:var(--spacing-primitives-spacing-16)}
.orphan-cards .amg-card--horizontal .amg-card__content ul{margin-bottom:var(--spacing-primitives-spacing-24);margin-left:var(--spacing-primitives-spacing-4)}
.orphan-cards .amg-card--horizontal .amg-card__actions{padding-bottom:var(--spacing-primitives-spacing-56)}
.orphan-cards .amg-card--horizontal .amg-card__actions a iconify-icon{font-size:.625rem !important}
.orphan-cards .amg-card--horizontal .amg-card__content{gap:0;z-index:1}
.orphan-cards .amg-card--horizontal .amg-card__content .amg-card__actions,.orphan-cards .amg-card--horizontal .amg-card__content .button,.orphan-cards .amg-card--horizontal .amg-card__content .cmp-button,.orphan-cards .amg-card--horizontal .amg-card__content .cmp-button a{max-width:15.625rem;width:100%}
@media(max-width:767px){.orphan-cards .amg-card--horizontal{flex-direction:column}
.orphan-cards .amg-card--horizontal .amg-card__media{max-width:100%}
.orphan-cards .amg-card--horizontal .amg-card__content .amg-card__actions,.orphan-cards .amg-card--horizontal .amg-card__content .button,.orphan-cards .amg-card--horizontal .amg-card__content .cmp-button,.orphan-cards .amg-card--horizontal .amg-card__content .cmp-button a{margin:0 auto}
.orphan-cards .amg-card--horizontal .amg-card__actions{padding-bottom:var(--spacing-primitives-spacing-16)}
}
@media(max-width:64rem){.orphan-cards{gap:1.875rem;display:flex;flex-direction:column}
}
@media(max-width:767px){.amg-card-container{padding:0}
.amg-card--horizontal .amg-card__media{max-width:100%;margin:0 auto}
.home-nsclc-bg .amg-card .amg-card__media{margin:var(--spacing-primitives-spacing-18) auto 0}
.home-nsclc-bg .amg-card__content{padding:var(--spacing-primitives-spacing-16) 0 var(--spacing-primitives-spacing-32) 0}
.real-word-card .amg-card__body ul{padding-left:var(--spacing-primitives-spacing-24)}
.custome-ul-list{padding-inline:0}
.download-resource-container .amg-section-with-slots [slot=content-block-02] .amg-card__media{padding-bottom:var(--spacing-primitives-spacing-18)}
.download-resource-container .amg-section-with-slots [slot=content-block-02] .amg-card__content{padding-top:var(--spacing-primitives-spacing-24)}
.download-resource-container .amg-section-with-slots .amg-section-with-slots__content{gap:var(--spacing-primitives-spacing-32)}
.download-resource-container .amg-card__content a{padding-inline:var(--spacing-primitives-spacing-12)}
.download-resource-container .amg-card__actions a{padding-inline:var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-52)}
.while-kras-card .amg-card__body ul{padding-left:var(--spacing-primitives-spacing-40)}
.home-nsclc-bg .amg-card__content{padding:var(--spacing-primitives-spacing-16) 0 var(--spacing-primitives-spacing-32) 0}
.real-word-card .amg-card__body ul{padding-left:var(--spacing-primitives-spacing-24)}
.custome-ul-list{padding-inline:0}
.download-resource-container .amg-section-with-slots [slot=content-block-02] .amg-card__media{padding-bottom:var(--spacing-primitives-spacing-18);margin-inline:auto}
.download-resource-container .amg-section-with-slots [slot=content-block-02] .amg-card__media img{width:26.875rem}
.download-resource-container .amg-section-with-slots [slot=content-block-02] .amg-card__content{padding-top:var(--spacing-primitives-spacing-24)}
.download-resource-container .amg-section-with-slots .amg-section-with-slots__content{gap:var(--spacing-primitives-spacing-32)}
.download-resource-container .amg-card__content a{padding-inline:var(--spacing-primitives-spacing-12)}
.while-kras-card .amg-card__body ul{padding-left:var(--spacing-primitives-spacing-40)}
.once-daily-card{margin-inline:var(--spacing-primitives-spacing-16);background:none !important;position:relative;border-radius:var(--brand-primitives-corner-radius-base-radius-base)}
.once-daily-card .amg-card__content{padding-inline:var(--spacing-primitives-spacing-12);text-align:center;background:var(--background-gradient-discover-page);padding-block:var(--spacing-primitives-spacing-80);border-radius:var(--brand-primitives-corner-radius-base-radius-base);position:relative;top:4.6875rem}
.once-daily-card .amg-card__content .amg-card__body{padding-block:var(--spacing-primitives-spacing-12)}
.once-daily-card .amg-card__media{position:absolute;left:50%;transform:translateX(-50%);z-index:9}
.first-sec-last-card .amg-section-with-slots__content{gap:var(--spacing-primitives-spacing-24);max-width:100%}
.first-sec-last-card .amg-section-with-slots__content .amg-card{min-height:unset;padding-bottom:0}
.support-resources-intro{padding-inline:0;margin-inline:0;width:100%;max-width:100%}
.support-resource-card{gap:var(--spacing-primitives-spacing-18);padding-bottom:var(--spacing-primitives-spacing-18)}
.support-resource-card .amg-card__content{padding-inline:0}
.oral-kras-bg-grad{padding:var(--spacing-primitives-spacing-32);text-align:left}
.confirm-dose{padding-inline:0}
}
:root{--gradient-primary-bg-gradient-with-opacity:linear-gradient(270deg,rgba(30,86,126,0.9) 0,rgba(105,185,175,0.9) 100%);--gradient-light-bg-gradient-with-opacity:linear-gradient(to top,rgba(255,255,255,1),rgba(237,255,253,1));--component-theme-light-surface-system-text-error-1:#e01029;--inpage-nav-gradient:linear-gradient(0,var(--component-theme-light-surface-interactive-navigation-in-page-nav-strong-background-default,#fff) 0,var(--component-theme-light-surface-interactive-navigation-in-page-nav-strong-background-default,#fff) 100%),var(--component-theme-light-surface-interactive-navigation-in-page-nav-strong-background-base,#ebf2e4);--text-shadow:.5px .5px 0 var(--brand-primitives-color-neutral-dark-base);--top-navigation-font-size:12px;--top-navigation-font-size:11px;--typography-headings-body-inline-3-font-size-10:10px;--connect-with-amgen-button-shadow:0 var(--spacing-primitives-spacing-4) var(--spacing-primitives-spacing-4) var(--spacing-primitives-spacing-0) var(--brand-primitives-color-neutral-dark-alpha-24);--pagination-background-color:#eaedec;--scroll-track-bacground:linear-gradient(0,var(--Interactive-Base-Low-Prominence-background-default,rgba(30,86,126,0.48)) 0,var(--Interactive-Base-Low-Prominence-background-default,rgba(30,86,126,0.48)) 100%),var(--Interactive-Base-Low-Prominence-background-active,#fff);--section-header-background-color:linear-gradient(to right,#eb2244 25%,transparent 25%);--section-header-background-color-large-screen:linear-gradient(to right,#eb2244 42%,transparent 42%);--section-header-background-color-med-screen:linear-gradient(to right,#eb2244 38%,transparent 38%);--section-header-background-color-dose-sec:linear-gradient(to right,#eb2244 15%,transparent 15%);--section-header-background-color-discover-page-discover-sec:linear-gradient(to bottom,#fff 0,#fff 2rem,transparent 2rem,transparent 100%),linear-gradient(to right,#eb2244 35%,transparent 35%);--support-text-reveresd:#6d6d6c;--gradient-primary-bg-gradient-with-support:linear-gradient(270deg,#0cbce0 0,#236ab1 100%);--gradient-primary-bg-gradient-with-support-hover:linear-gradient(to right,#0063c3 4%,#00bce4 93%);--home-mobile-cta-section-background-gard:linear-gradient(180deg,#1e567e 0,#69b9af 100%);--card-bottom-line:#6d6c6ccc;--btn-box-shadow:0 4px 4px 0 rgba(0,0,0,0.25);--background-gradient-discover-page:linear-gradient(90deg,#fff 0,#fff 5%,rgba(105,185,175,0.9) 15%,rgba(30,86,126,0.9) 100%) !important;--spacing-primitives-spacing-20:20px;--gradient-light-bg-gradient-with-opacity-reverse:linear-gradient(0,#edfffd 0,#fff 100%);--tab-btn-box-shadow:0 4px 16px 0,rgba(109,108,108,0.16);--tabs-background-clr:#6d6c6c80}
@media((min-width:156.25rem) and (max-width:343.75rem)){:root{--section-header-background-color-discover-page-discover-sec:linear-gradient(to bottom,#fff 0,#fff 2rem,transparent 2rem,transparent 100%),linear-gradient(to right,#eb2244 40%,transparent 40%)}
}
@media(max-width:61.9375rem){:root{--typography-headings-body-inline-3-font-size-10:12px}
}
@media(max-width:767px){:root{--top-navigation-font-size:10px;--background-gradient-discover-page:linear-gradient(270deg,rgba(30,86,126,0.9) 0,rgba(105,185,175,0.9) 100%) !important}
}
.amg-btn:not(.amg-btn--tertiary):not(.amg-cta-banner__buttons .amg-btn){background-color:var(--component-theme-light-surface-interactive-base-high-prominence-text-icon-interactive);border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-primary-dark-base);color:var(--brand-primitives-color-primary-dark-base)}
.amg-btn:not(.amg-btn--tertiary):not(.amg-cta-banner__buttons .amg-btn):hover{background-color:var(--brand-primitives-color-primary-dark-base);color:var(--component-theme-light-surface-interactive-base-high-prominence-text-icon-interactive)}
.amg-btn:not(.amg-btn--tertiary):not(.amg-cta-banner__buttons .amg-btn) amg-icon iconify-icon{color:var(--brand-primitives-color-secondary-light-tint-2)}
.next-page-cta{margin-block:var(--spacing-primitives-spacing-48) var(--spacing-primitives-spacing-40)}
.next-page-cta a iconify-icon{font-size:.625rem !important}
.right-arrow-size a iconify-icon{font-size:.625rem !important}
.right-arrow-size a.amg-btn{box-shadow:0 var(--spacing-primitives-spacing-4) var(--spacing-primitives-spacing-4) 0 var(--brand-primitives-color-neutral-dark-alpha-24);max-width:92%;line-height:normal;text-align:center}
.button a.amg-btn:not(.amg-btn--tertiary){display:block;position:relative;text-align:center;padding-inline:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-60);box-shadow:var(--btn-box-shadow)}
.amg-btn{outline:0}
.error-page .stack a.amg-btn{padding-inline:var(--spacing-primitives-spacing-24) 0;text-align:center}
.for-hcp-stack .button a.amg-btn,.commercial-insu .button a.amg-btn,.amg-hero .button a.amg-btn{padding-inline:var(--spacing-primitives-spacing-24)}
.button a.amg-btn amg-icon{position:absolute;right:var(--spacing-primitives-spacing-24);top:52%;transform:translateY(-50%)}
.next-page-cta a.amg-btn{padding-inline:var(--spacing-primitives-spacing-32) var(--spacing-primitives-spacing-48)}
.next-page-cta a.amg-btn amg-icon{right:var(--spacing-primitives-spacing-16)}
@media(max-width:767px){.next-page-cta{max-width:100%;margin-inline:auto;width:100%;margin-block:var(--spacing-primitives-spacing-18) var(--spacing-primitives-spacing-32)}
.next-page-cta a.amg-btn{text-align:center}
.button a.amg-btn:not(.amg-btn--tertiary){padding-inline:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-40);width:100%}
.button a.amg-btn amg-icon{right:var(--spacing-primitives-spacing-28)}
}
.amg-footer{background:var(--component-theme-dark-surface-interactive-navigation-footer-background-base)}
.amg-footer .amg-footer-legal{background:transparent;max-width:86rem;margin:0 auto;gap:var(--spacing-primitives-spacing-24);padding-inline:var(--spacing-primitives-spacing-16)}
.amg-footer .amg-footer-legal .amg-link{color:var(--brand-primitives-color-neutral-light-1)}
.amg-footer .amg-footer-legal .amg-link:hover{text-decoration:underline;color:var(--brand-primitives-color-neutral-light-1)}
.amg-footer .amg-footer-legal .amg-footer-legal__content{max-width:62.8125rem}
.amg-footer .amg-footer-legal .amg-footer-legal__nav{padding-bottom:var(--spacing-primitives-spacing-32)}
.amg-footer .amg-footer-legal .amg-footer-legal__nav ul,.amg-footer .amg-footer-legal .amg-footer-legal__nav ul li{gap:var(--spacing-primitives-spacing-12)}
.amg-footer .amg-footer-legal--logo-left .amg-footer-legal__logo{padding-right:0}
.amg-footer .amg-social-links__icons .amg-icon-btn--round{padding:var(--spacing-primitives-spacing-8)}
.amg-footer .amg-social-links__icons .amg-icon-btn--round:hover{transform:scale(1.1)}
@media(max-width:767px){.amg-footer .amg-footer-legal .amg-footer-legal__content{order:2}
.amg-footer .amg-footer-legal .amg-footer-legal__social-links{order:3}
.amg-footer .amg-footer-legal .amg-footer-legal__logo{order:1}
}
@media(max-width:767px){.amg-footer .amg-footer-legal .amg-align--center{justify-content:start}
.amg-footer .amg-footer-legal .amg-footer-legal__nav{padding-bottom:0}
}
.connect-with-amgen input:not(.amg-hero__search-field-wrapper *)::placeholder,.connect-with-amgen textarea:not(.amg-hero__search-field-wrapper *)::placeholder,.connect-with-amgen label:not(.amg-hero__search-field-wrapper *),.connect-with-amgen option:not(.amg-hero__search-field-wrapper *),.connect-with-amgen select[name]:not(.amg-hero__search-field-wrapper *),.connect-with-amgen input[name]:not(.amg-hero__search-field-wrapper *){color:var(--brand-primitives-color-neutral-dark-shade-2);font:var(--f-p-12);line-height:var(--system-primitives-typography-sizing-leading-paragraph-leading-10-16)}
.connect-with-amgen label:not(.amg-hero__search-field-wrapper *){color:var(--brand-primitives-color-neutral-dark-shade-3)}
.connect-with-amgen input:not(.amg-hero__search-field-wrapper *),.connect-with-amgen select:not(.amg-hero__search-field-wrapper *){border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-neutral-dark-shade-3);background:0;border-radius:0;padding:.6875rem .9375rem}
.connect-with-amgen .amg-field--error:not(.amg-hero__search-field-wrapper *),.connect-with-amgen .amg-numeric-input__input:not(.amg-hero__search-field-wrapper *){border-color:var(--component-theme-light-surface-system-text-error-1)}
.connect-with-amgen .amg-error-success-message__text:not(.amg-hero__search-field-wrapper *){color:var(--component-theme-light-surface-system-text-error-1);font:var(--f-p-12);font-style:italic;line-height:1.3125rem;letter-spacing:-0.015rem}
.connect-with-amgen .amg-error-success-message--success .amg-error-success-message__text:not(.amg-hero__search-field-wrapper *){color:var(--component-theme-light-surface-system-text-success)}
.connect-with-amgen .container.aem-GridColumn--default--12{max-width:100% !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .aemform{max-width:63.75rem;margin:0 auto var(--spacing-primitives-spacing-32);padding-inline:var(--spacing-primitives-spacing-16)}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form{max-width:100%}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .text.base div>p .npi-modal-open{color:var(--component-theme-light-surface-interactive-base-outline-default);text-decoration:underline}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .text.base div>p{font-size:var(--typography-headings-body-body-1-font-size);padding-bottom:var(--spacing-primitives-spacing-16)}
.connect-with-amgen .cmp-adaptiveform-fragment__label-container + .aem-Grid{display:flex !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .textinput{width:50% !important;padding-bottom:var(--spacing-primitives-spacing-24)}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .textinput.aem-GridColumn--offset--default--1{margin-left:var(--spacing-components-desktop-0) !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form input{width:96.5%;height:3rem}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown{margin-left:var(--spacing-components-desktop-0) !important;width:50% !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown select{width:96.5%;height:3rem;appearance:none;background-image:url(data:image/svg+xml;base64,PHN2ZyB3aWR0aD0iMTYiIGhlaWdodD0iMTAiIHZpZXdCb3g9IjAgMCAxNiAxMCIgZmlsbD0ibm9uZSIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj4KPHBhdGggZD0iTTggOS44NjY2N0wwIDEuODY2NjdMMS44NjY2NyAwTDggNi4xMzMzM0wxNC4xMzMzIDBMMTYgMS44NjY2N0w4IDkuODY2NjdaIiBmaWxsPSIjMUU1NjdFIi8+Cjwvc3ZnPg==);background-position:right;background-repeat:no-repeat;background-size:3.125rem .625rem}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown.aem-GridColumn--offset--default--0,.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown.aem-GridColumn--offset--default--1{width:100% !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown.aem-GridColumn--default--6{width:50% !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .fragment.panelcontainer + .checkbox.base{padding-block:var(--spacing-primitives-spacing-48) var(--spacing-primitives-spacing-12)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container{display:flex;align-items:baseline;position:relative;margin-left:var(--spacing-primitives-spacing-18)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container input{width:0;height:0;position:absolute;padding:0;margin:0;border:0}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container input:after{content:"";width:1.25rem;height:1.25rem;display:block;border:var(--borders-weight-weight-2) solid var(--component-theme-light-surface-interactive-base-outline-default);border-radius:var(--brand-primitives-corner-radius-forms-radius-checkboxes)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container input:checked:after{background:var(--brand-primitives-color-primary-dark-shade-1);border-radius:4px;border:var(--borders-weight-weight-2) solid var(--component-theme-light-surface-interactive-base-outline-default)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container input:checked:before{content:"";top:var(--spacing-primitives-spacing-6);height:var(--spacing-primitives-spacing-4);width:var(--spacing-primitives-spacing-12);border-width:0 0 var(--borders-weight-weight-2) var(--borders-weight-weight-2);border-style:solid;left:var(--spacing-primitives-spacing-4);border-color:transparent transparent var(--brand-primitives-color-neutral-light-base) var(--brand-primitives-color-neutral-light-base);transform:rotate(-45deg);display:block;position:absolute}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container label.cmp-adaptiveform-checkbox__label{padding-left:var(--spacing-primitives-spacing-28)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container label.cmp-adaptiveform-checkbox__label p a{color:var(--component-theme-light-surface-interactive-base-outline-default)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container label.cmp-adaptiveform-checkbox__label p.mt-4{margin-left:-1.75rem}
.connect-with-amgen .container.aem-GridColumn--default--12 .button button{box-shadow:var(--connect-with-amgen-button-shadow);background:var(--brand-primitives-color-neutral-light-base);width:16.875rem;padding-block:var(--spacing-primitives-spacing-16);border-radius:var(--brand-primitives-corner-radius-base-radius-outside);border:var(--borders-weight-weight-2) solid var(--component-theme-light-surface-interactive-base-outline-default);font-size:var(--typography-headings-intro-intro-2-font-size);font-weight:var(--brand-primitives-typography-styles-cta-base-weight);color:var(--component-theme-light-surface-interactive-base-outline-default);margin-top:var(--spacing-primitives-spacing-24);line-height:100%}
.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] label:not(.cmp-adaptiveform-checkbox__label),.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] .cmp-adaptiveform-textinput__label-container,.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] .cmp-adaptiveform-textinput__errormessage,.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] .cmp-adaptiveform-emailinput__errormessage,.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] .cmp-adaptiveform-telephoneinput__errormessage,.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] .cmp-adaptiveform-dropdown__errormessage{color:var(--brand-primitives-color-secondary-light-tint-2);font-style:italic}
.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] input,.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] select{border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-secondary-light-tint-2)}
.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] .cmp-adaptiveform-checkbox__errormessage{padding-top:var(--spacing-primitives-spacing-16);padding-left:var(--spacing-primitives-spacing-48);color:var(--brand-primitives-color-secondary-light-tint-2);font-style:italic;padding-bottom:var(--spacing-components-desktop-6)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox [data-cmp-valid=false] input:after{border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-secondary-light-tint-2)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog{max-width:34.5rem !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .button button{box-shadow:none;border:0;margin-top:0;width:var(--spacing-primitives-spacing-24);padding:0}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .button button p{font-size:3rem;font-weight:400;position:relative}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content{border-radius:0 !important;padding:var(--spacing-primitives-spacing-24)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container{flex-direction:column;display:flex}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container .text{padding-bottom:var(--spacing-primitives-spacing-12)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container .cmp-container__label-container{display:flex}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container .cmp-container__label-container + .button.base{display:flex;order:-1;justify-content:end;height:1.875rem}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container .cmp-container__label-container label.cmp-container__label{font-size:var(--typography-headings-headline-4-font-size);line-height:var(--typography-headings-headline-4-leading);font-weight:var(--brand-primitives-typography-styles-headings-emphasis-weight);color:var(--component-theme-light-surface-static-text-icon-text-standard);padding-bottom:var(--spacing-primitives-spacing-12)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container .textinput,.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container .dropdown,.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container select,.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container input{min-width:100%;width:100%}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .cmp-container .textinput.base + .button button{box-shadow:var(--connect-with-amgen-button-shadow);background:var(--brand-primitives-color-neutral-light-base);width:100%;padding-block:var(--spacing-primitives-spacing-16);border-radius:var(--brand-primitives-corner-radius-base-radius-outside);border:var(--borders-weight-weight-2) solid var(--component-theme-light-surface-interactive-base-outline-default);font-size:var(--typography-headings-intro-intro-2-font-size);font-weight:var(--brand-primitives-typography-styles-cta-base-weight);color:var(--component-theme-light-surface-interactive-base-outline-default);margin-block:var(--spacing-primitives-spacing-24)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content .textinput + .dropdown{padding-bottom:var(--spacing-primitives-spacing-24)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show table.results-table thead tr{border-top:var(--borders-weight-weight-1) solid var(--component-theme-light-surface-interactive-base-outline-default);border-bottom:var(--borders-weight-weight-1) solid var(--component-theme-light-surface-interactive-base-outline-default);align-items:center}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show table.results-table thead tr th{vertical-align:middle;padding:var(--spacing-primitives-spacing-18) var(--spacing-primitives-spacing-12);font-size:var(--typography-headings-body-body-2-font-size);color:var(--brand-primitives-color-neutral-dark-base);line-height:var(--typography-headings-body-body-1-leading)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show table.results-table tbody tr{border-bottom:var(--borders-weight-weight-1) solid var(--component-theme-light-surface-interactive-base-outline-default)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show table.results-table tbody tr td{padding:var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-8);font-size:var(--typography-headings-body-body-2-font-size);color:var(--brand-primitives-color-neutral-dark-base)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show table.results-table tbody tr td a.add-to-form-link{color:var(--component-theme-light-surface-interactive-base-outline-default);position:relative;left:var(--spacing-primitives-spacing-12)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show table.results-table tbody tr td a.add-to-form-link:before{content:"+";position:absolute;color:var(--component-theme-light-surface-interactive-base-outline-default);font-size:var(--typography-headings-intro-intro-2-font-size);left:calc(var(--spacing-primitives-spacing-24) * -1);top:calc(var(--spacing-primitives-spacing-4) * -1)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .table-heading-container h5{font-size:var(--typography-headings-headline-4-font-size);color:var(--component-theme-light-surface-interactive-base-outline-default);font-weight:var(--brand-primitives-typography-styles-headings-alt-emphasis-weight);line-height:var(--typography-headings-headline-4-leading)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .pagination-container{margin-inline:auto}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .paginationjs-pages ul{display:flex;gap:var(--spacing-primitives-spacing-16);justify-content:center;align-items:center}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .paginationjs-pages ul li.paginationjs-page a{display:flex;width:auto;height:auto;min-width:1.875rem;min-height:1.875rem;color:var(--brand-primitives-color-neutral-dark-shade-3);font-size:var(--typography-headings-body-body-1-font-size);font-weight:600;font-stretch:normal;font-style:normal;text-align:center;border-radius:.25rem;align-items:center;justify-content:center;background:var(--pagination-background-color)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .paginationjs-pages ul li.paginationjs-page.active a{background-color:var(--brand-primitives-color-neutral-light-base);color:var(--component-theme-light-surface-interactive-base-outline-default);border:solid var(--borders-weight-weight-1) var(--component-theme-light-surface-interactive-base-outline-default)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .paginationjs-pages ul li.paginationjs-prev a,.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .paginationjs-pages ul li.paginationjs-next a{font-size:var(--typography-headings-headline-2-font-size);line-height:var(--spacing-primitives-spacing-24);color:var(--brand-primitives-color-primary-dark-shade-1)}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .table-heading-error-container h5,.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .table-heading-error-container p{font-size:var(--typography-headings-body-body-1-font-size);font-weight:400;font-style:italic;line-height:1.75;letter-spacing:normal;text-align:left;color:var(--component-theme-light-surface-system-text-error-1) !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .table-heading-error-container + nav.pagination-container{display:none}
.connect-with-amgen .container.aem-GridColumn--default--12 .cmp-adaptiveform-radiobutton[data-name=suggested_address]{border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-secondary-light-tint-2);padding:var(--spacing-primitives-spacing-24);margin-bottom:var(--spacing-primitives-spacing-16)}
.connect-with-amgen .container.aem-GridColumn--default--12 .cmp-adaptiveform-radiobutton[data-name=suggested_address] .cmp-adaptiveform-radiobutton__label-container label{color:var(--brand-primitives-color-secondary-light-tint-2);font-size:var(--typography-headings-body-body-1-font-size);font-style:italic}
.connect-with-amgen .container.aem-GridColumn--default--12 .cmp-adaptiveform-radiobutton[data-name=suggested_address] .cmp-adaptiveform-radiobutton__widget{display:flex;gap:var(--spacing-primitives-spacing-32)}
.connect-with-amgen .container.aem-GridColumn--default--12 .cmp-adaptiveform-radiobutton[data-name=suggested_address] .cmp-adaptiveform-radiobutton__widget .cmp-adaptiveform-radiobutton__option{border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-neutral-dark-shade-3);padding:var(--spacing-primitives-spacing-16);margin-top:var(--spacing-primitives-spacing-16)}
.connect-with-amgen .container.aem-GridColumn--default--12 .cmp-adaptiveform-radiobutton[data-name=suggested_address] .cmp-adaptiveform-radiobutton__widget .cmp-adaptiveform-radiobutton__option label.cmp-adaptiveform-radiobutton__option-label{display:flex;gap:var(--spacing-primitives-spacing-16)}
.connect-with-amgen .container.aem-GridColumn--default--12 .cmp-adaptiveform-radiobutton[data-name=suggested_address] .cmp-adaptiveform-radiobutton__widget .cmp-adaptiveform-radiobutton__option label.cmp-adaptiveform-radiobutton__option-label input{width:1.25rem;height:var(--spacing-primitives-spacing-16)}
.connect-with-amgen .container.aem-GridColumn--default--12 .cmp-adaptiveform-radiobutton[data-name=suggested_address] p.radio-title{color:var(--brand-primitives-color-neutral-dark-shade-3);padding-bottom:var(--spacing-primitives-spacing-16)}
.connect-with-amgen .container.aem-GridColumn--default--12 .thank-you-message,.connect-with-amgen .container.aem-GridColumn--default--12 .submission-error-message{margin-bottom:var(--spacing-primitives-spacing-32)}
.connect-with-amgen .container.aem-GridColumn--default--12 h3{color:var(--brand-primitives-color-section-section-bg-dark-1);font-size:var(--typography-headings-headline-3-font-size);font-weight:700;margin-bottom:var(--spacing-primitives-spacing-18)}
.connect-with-amgen .container.aem-GridColumn--default--12 h3 + p{color:var(--brand-primitives-color-section-section-bg-dark-1);font-size:var(--typography-headings-intro-intro-2-font-size);margin-bottom:var(--spacing-primitives-spacing-16);line-height:normal}
.connect-with-amgen .container.aem-GridColumn--default--12 h3 + p + p a{box-shadow:var(--connect-with-amgen-button-shadow);background:var(--brand-primitives-color-neutral-light-base);display:block;width:max-content;padding-inline:var(--spacing-primitives-spacing-24);padding-block:var(--spacing-primitives-spacing-16);border-radius:var(--brand-primitives-corner-radius-base-radius-outside);border:var(--borders-weight-weight-2) solid var(--component-theme-light-surface-interactive-base-outline-default);font-size:var(--typography-headings-body-body-1-font-size);font-weight:var(--brand-primitives-typography-styles-cta-base-weight);color:var(--component-theme-light-surface-interactive-base-outline-default);margin-top:var(--spacing-primitives-spacing-24);text-align:center;position:relative}
.connect-with-amgen .container.aem-GridColumn--default--12 h3 + p + p a:before{content:"";background-image:url(data:image/svg+xml;base64,PHN2ZyB3aWR0aD0iNiIgaGVpZ2h0PSIxMCIgdmlld0JveD0iMCAwIDYgMTAiIGZpbGw9Im5vbmUiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+CjxwYXRoIGQ9Ik01IDEwTDAgNUw1IDBMNS44ODc1IDAuODg3NUwxLjc3NSA1TDUuODg3NSA5LjExMjVMNSAxMFoiIGZpbGw9IiNFNzI0NDQiLz4KPC9zdmc+);position:absolute;background-size:contain;width:100%;height:var(--spacing-primitives-spacing-12);background-repeat:no-repeat;top:50%;transform:translateY(-50%);right:-0.75rem}
.connect-with-amgen .container.aem-GridColumn--default--12 h3 + p + p a h3 + p + p a{color:var(--brand-primitives-color-section-section-bg-dark-1)}
@media(max-width:767px){.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .textinput{width:100% !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form input:not([type=checkbox]){width:100%}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown select{width:100%}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown.aem-GridColumn--offset--default--0,.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown.aem-GridColumn--offset--default--1{padding-bottom:var(--spacing-primitives-spacing-24)}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .dropdown.aem-GridColumn--default--6{width:100% !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .cmp-adaptiveform-button{width:auto;margin:0}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content{overflow-y:auto}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content::-webkit-scrollbar{width:.25rem;border-radius:62.5rem}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content::-webkit-scrollbar-track{background:var(--scroll-track-bacground);border-radius:62.5rem}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content::-webkit-scrollbar-thumb{background:var(--component-theme-light-surface-static-text-icon-text-standard);border-radius:62.5rem}
.connect-with-amgen .container.aem-GridColumn--default--12 .modal.show .modal-dialog .modal-content::-webkit-scrollbar-thumb:hover{background:var(--brand-primitives-color-section-section-bg-dark-3)}
.connect-with-amgen .container.aem-GridColumn--default--12 .button button{margin-top:0}
.connect-with-amgen .container.aem-GridColumn--default--12 .fragment.panelcontainer + .checkbox.base{padding-block:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-12)}
.connect-with-amgen .container.aem-GridColumn--default--12 .checkbox .cmp-adaptiveform-checkbox__widget-container{margin-left:0}
.connect-with-amgen .container.aem-GridColumn--default--12 [data-cmp-valid=false] .cmp-adaptiveform-checkbox__errormessage{padding-left:var(--spacing-primitives-spacing-28)}
.connect-with-amgen .hero{display:none}
}
amg-header .amg-indication-banner{max-width:76.875rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
amg-header .amg-indication-banner .amg-indication-banner__content{max-width:100%;margin:0 auto}
amg-header .amg-indication-banner .amg-indication-banner__text--collapsed .pb-3{padding-bottom:0 !important}
amg-header .amg-header--desktop .amg-utility-bar{align-items:center;padding-block:0;height:2.625rem;padding-inline:var(--spacing-primitives-spacing-16);position:static}
amg-header .amg-header--desktop .amg-utility-bar .amg-utility-disclaimer{display:none}
amg-header .amg-header__secondary-nav{display:none}
amg-header .amg-utility-bar__links{align-items:center;max-width:76.875rem;width:100%;margin:0 auto;justify-content:flex-end}
amg-header .amg-utility-bar__links li:not(:last-child):hover{background-color:var(--brand-primitives-color-neutral-dark-base)}
amg-header .amg-utility-bar__links li:not(:last-child):hover .amg-link{color:var(--brand-primitives-color-neutral-light-base)}
amg-header .amg-utility-bar__links .amg-link{text-transform:uppercase;text-decoration:underline;font-size:var(--top-navigation-font-size)}
amg-header .amg-utility-bar__links .amg-btn{padding:var(--spacing-primitives-spacing-6) var(--spacing-primitives-spacing-24);height:1.875rem;line-height:normal}
amg-header .amg-utility-bar__links .amg-utility-bar__end-cta{padding:0}
amg-header .amg-utility-bar__links .amg-utility-bar__end-cta .amg-btn:hover{border:var(--borders-weight-weight-2) solid color-mix(in srgb,var(--component-theme-light-surface-interactive-ctas-state-scrims-hover-focus-strong),var(--component-theme-light-surface-interactive-ctas-low-prominence-background-default))}
amg-header .amg-navbar__items{gap:var(--spacing-primitives-spacing-32);text-align:center;align-items:center}
amg-header .amg-menu-link{padding:0;display:block}
amg-header .amg-menu-link.amg-link--active{border-bottom:var(--brand-primitives-borders-weight-weight-3) solid var(--component-theme-light-surface-interactive-base-underline)}
amg-header .amg-header__nav{max-width:76.875rem;margin:0 auto;box-shadow:none;padding-inline:var(--spacing-primitives-spacing-16);justify-content:space-between}
amg-header .amg-header__nav .amg-logo img{min-height:max-content;width:13.75rem}
amg-header .amg-cta-banner--has-logo{justify-content:start;max-width:76.875rem;margin:0 auto}
amg-header .amg-cta-banner__buttons{position:absolute;bottom:1rem;gap:var(--spacing-primitives-spacing-8);transform:translateX(-1rem)}
amg-header .amg-cta-banner__buttons :first-child{width:5.75rem;height:2.625rem;font-size:var(--typography-headings-body-inline-2-font-size);border-radius:var(--brand-primitives-corner-radius-button-edge-button) var(--brand-primitives-corner-radius-button-edge-button) 0 0;border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-secondary-light-tint-2);background:var(--brand-primitives-color-secondary-light-tint-2);box-shadow:0 .25rem 1rem 0 var(--brand-primitives-color-neutral-dark-alpha-48);color:var(--brand-primitives-color-neutral-light-base);text-decoration:underline}
amg-header .amg-cta-banner__buttons :last-child{width:5.375rem;height:2.625rem;text-decoration:underline;font-size:var(--typography-headings-body-inline-3-font-size-10);color:var(--brand-primitives-color-primary-dark-base);text-align:center;border-radius:var(--brand-primitives-corner-radius-button-edge-button) var(--brand-primitives-corner-radius-button-edge-button) 0 0;border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-accent-3-dark-shade-2);background:var(--brand-primitives-color-accent-3-dark-shade-2);box-shadow:0 .25rem 1rem 0 var(--brand-primitives-color-neutral-dark-alpha-48)}
@media(min-width:62rem) and (max-width:64rem){amg-header .amg-utility-bar__links .amg-link{font-size:var(--top-navigation-font-size)}
}
@media(max-width:61.9375rem){.nsclc-header{z-index:9999;position:relative}
amg-header .amg-header__secondary-nav{display:block}
amg-header .amg-header__nav{padding-block:0}
amg-header .amg-cta-banner__buttons{position:static;width:100%;transform:none;justify-content:space-between}
amg-header .amg-cta-banner__buttons .amg-btn{box-shadow:none}
amg-header .amg-cta-banner__buttons .amg-btn:first-child{width:48.5%}
amg-header .amg-cta-banner__buttons .amg-btn:last-child{width:48.5%;padding-inline:var(--spacing-primitives-spacing-12)}
amg-header .amg-utility-bar__links{flex-direction:row;flex-wrap:wrap}
amg-header .amg-utility-bar__links li{flex-basis:48%;text-align:center}
amg-header .amg-utility-bar__links .amg-link{width:100%;justify-content:center;padding-inline:0}
amg-header .amg-utility-bar__links .amg-utility-bar__end-cta{display:none}
amg-header .amg-navbar__items{align-items:flex-start;text-align:left}
amg-header .amg-header__mobile-primary-nav a.amg-btn{display:block;max-width:100%;width:90%;text-align:center;margin:0 auto;border-bottom:0}
amg-header .amg-utility-bar__links .amg-btn{width:100%;padding:var(--spacing-primitives-spacing-8) var(--spacing-primitives-spacing-24);font:var(--f-p-16);letter-spacing:-0.0234375rem}
amg-header .amg-header__mobile-primary-nav{padding:0}
amg-header .amg-header__mobile-primary-nav .amg-navbar{width:100%}
amg-header .amg-header__mobile-primary-nav .amg-navbar ul.amg-navbar__items{gap:0}
amg-header .amg-header__mobile-primary-nav .amg-navbar ul.amg-navbar__items li{padding:var(--spacing-primitives-spacing-16);border-bottom:var(--borders-weight-weight-1) solid var(--brand-primitives-color-neutral-light-tint-2);width:100%;position:relative}
amg-header .amg-header__mobile-primary-nav .amg-navbar ul.amg-navbar__items li:after{content:"";background-image:url(data:image/svg+xml;base64,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);position:absolute;width:.625rem;height:.9375rem;right:1rem;background-size:contain;top:50%;transform:translateY(-50%);background-repeat:no-repeat}
amg-header .amg-indication-banner__text--collapsed div p.pb-3{padding-bottom:0 !important}
amg-header .amg-popup--nav .amg-popup__body{border-top:.0625rem solid}
amg-header .amg-popup__header{align-items:center}
amg-header .amg-header__nav .amg-logo img{width:6.25rem}
amg-header amg-popup-nav .amg-logo--lg img{width:6.25rem}
amg-header .amg-popup.is-open .amg-popup__container{gap:0}
}
.amg-btn--edge-bottom{background:var(--component-theme-light-surface-assets-secondary-base);color:var(--brand-primitives-color-neutral-light-base);border:0;text-decoration:underline}
#nav-popup .amg-popup__container{padding:var(--spacing-primitives-spacing-48);gap:var(--spacing-primitives-spacing-16)}
#nav-popup .amg-popup__container .amg-popup__header-actions{position:absolute;top:1.25rem;right:1.25rem}
#nav-popup .amg-popup__container .amg-popup__nav-title{padding:0}
.amg-hero .amg-hero__content-col .amg-hero__text-section h1.amg-hero__text-section-title,.amg-hero .amg-hero__content-col .amg-hero__text-section p.amg-font-intro-3{color:var(--component-theme-dark-surface-static-text-icon-text-standard)}
.amg-hero .amg-hero__top-section--ratio-large{background-position:center top}
.amg-hero .amg-hero__top-section--ratio-large .amg-hero__cta-bar{padding:var(--spacing-components-desktop-0)}
.amg-hero .amg-hero__cta-bar-wrapper{padding:var(--spacing-components-desktop-0)}
.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar{border-radius:var(--brand-primitives-corner-radius-nav-nav-top);flex-direction:column-reverse;background:var(--gradient-primary-bg-gradient-with-opacity);margin-top:var(--spacing-primitives-spacing-32)}
.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__content-card-title,.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__content-card-text,.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__bottom-title{color:var(--component-theme-dark-surface-static-text-icon-text-standard)}
.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__content-card--no-bg:focus{border:0}
.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__content-card--no-bg:hover{background:0}
.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__content-cards{padding-inline:var(--spacing-primitives-spacing-16)}
.amg-hero .amg-hero__cta-bar{padding:var(--spacing-primitives-spacing-56) var(--spacing-components-desktop-0) var(--spacing-primitives-spacing-32)}
.amg-hero .amg-hero__content-cards{max-width:65rem;margin:0 auto;grid-template-columns:repeat(3,1fr);gap:var(--spacing-primitives-spacing-32)}
.amg-hero .amg-hero__content-cards .amg-hero__content-card{padding:var(--spacing-components-desktop-0)}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group{border-right:var(--borders-weight-weight-1) solid var(--brand-primitives-color-neutral-light-alpha-64)}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group:last-child{border-right:0}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group:nth-child(2) .amg-hero__content-card-title{padding-right:var(--spacing-primitives-spacing-64)}
.amg-hero .amg-hero__content-card-group{flex-direction:column;border-left:0}
.amg-hero .amg-hero__content-card-group .amg-align--center{width:100%;padding-top:2.625rem;justify-content:left}
.amg-hero .amg-hero__content-card-group .amg-align--center .amg-btn{width:100%;max-width:88%;padding-block:var(--spacing-primitives-spacing-16);position:relative;font-size:var(--typography-headings-cta-large-font-size);line-height:var(--typography-headings-cta-large-leading);padding-inline:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-56)}
.amg-hero .amg-hero__content-card-group .amg-align--center .amg-btn amg-icon{position:absolute;right:var(--spacing-primitives-spacing-16)}
.amg-hero .amg-hero__content-card-group .amg-align--center .amg-btn amg-icon iconify-icon{font-size:.5625rem !important}
.amg-hero .amg-hero__content-card-group .amg-align--center .amg-btn amg-icon iconify-icon svg{width:.5625rem !important;height:.9375rem !important}
.amg-hero .amg-content-icon{background:0;width:4.875rem;padding:var(--spacing-components-desktop-0)}
.amg-hero .amg-content-icon img{width:4.875rem}
.amg-hero .hero-bottom-text{background:var(--gradient-primary-bg-gradient-with-opacity);padding-block:0 var(--spacing-primitives-spacing-56);position:relative}
.amg-hero .hero-bottom-text p{max-width:76.875rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16);color:var(--brand-primitives-color-neutral-light-base)}
.amg-hero .amg-hero__top-section--has-image .amg-hero__hero-content{align-items:flex-end;background:transparent}
.amg-hero .amg-hero__top-section--has-image .amg-hero__hero-content-inner{margin-bottom:var(--spacing-primitives-spacing-32)}
.amg-hero .amg-hero__hero-content .amg-align--center a{width:24.6875rem;line-height:normal}
.amg-hero .amg-hero__hero-content .amg-align--center a iconify-icon{font-size:var(--system-primitives-typography-sizing-font-size-font-10) !important;padding-left:var(--spacing-primitives-spacing-16)}
.amg-hero.inner-page-hero .amg-hero__top-section{aspect-ratio:5/1}
@media(max-width:767px){.lumakrashcp-hero{background-image:none !important}
.lumakrashcp-hero .amg-hero__top-section{background-size:contain;aspect-ratio:unset;padding-top:60%}
.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar{background:#fff;box-shadow:none;padding-inline:var(--spacing-primitives-spacing-32)}
.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__content-card-title,.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__content-card-text,.amg-hero .amg-hero__cta-bar-wrapper .amg-hero__cta-bar .amg-hero__bottom-title{color:var(--component-theme-light-surface-static-text-icon-text-standard)}
.amg-hero .amg-hero__text-section h1{padding-inline:var(--spacing-primitives-spacing-16);line-height:normal}
.amg-hero .amg-hero__with-image-row{padding-inline:var(--spacing-primitives-spacing-16)}
.amg-hero .amg-hero__content-card-wrapper{gap:var(--spacing-primitives-spacing-24)}
.amg-hero .amg-hero__content-cards{grid-template-columns:repeat(1,1fr)}
.amg-hero .amg-hero__content-cards .amg-content-icon img{display:none}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group .amg-divider{display:none}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group .amg-content-icon{background-repeat:no-repeat;background-size:contain;border-radius:0}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group:nth-child(1) .amg-content-icon{background-image:url(data:image/svg+xml;base64,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);width:4.6875rem;height:5rem}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group:nth-child(2) .amg-hero__content-card-title{padding-right:0}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group:nth-child(2) .amg-content-icon{background-image:url(data:image/svg+xml;base64,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);width:4.0625rem;height:4.6875rem}
.amg-hero .amg-hero__content-cards .amg-hero__content-card-group:nth-child(3) .amg-content-icon{background-image:url(data:image/svg+xml;base64,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);width:4.5rem;height:3.75rem}
.amg-hero .amg-hero__content-card-group .amg-align--center{padding-top:var(--spacing-primitives-spacing-16);justify-content:center}
.amg-hero .amg-hero__content-card-group .amg-align--center .amg-btn{box-shadow:0 .25rem 1rem 0 var(--brand-primitives-color-neutral-dark-alpha-24);font-size:var(--typography-headings-intro-intro-2-font-size);line-height:var(--typography-headings-intro-intro-2-font-size-leading);padding-inline:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-32)}
.amg-hero .hero-bottom-text{background:transparent;padding-bottom:var(--spacing-primitives-spacing-24)}
.amg-hero .hero-bottom-text p{color:var(--brand-primitives-color-section-section-bg-dark-1)}
.amg-hero .amg-hero__text-section p:first-child + p{padding-inline:var(--spacing-primitives-spacing-16)}
.amg-hero .amg-hero__top-section--has-image .amg-hero__hero-content{background:var(--home-mobile-cta-section-background-gard)}
.amg-hero .amg-hero__top-section--has-image .amg-hero__hero-content-inner{padding-block:var(--spacing-primitives-spacing-24);margin-bottom:0}
.amg-hero .amg-hero__top-section--has-image .amg-hero__hero-content-inner .amg-font-headline-6{font-size:var(--brand-primitives-channel-sizing-web-mobile-body-inline-2-font-size);line-height:var(--brand-primitives-channel-sizing-web-mobile-headline-4-leading)}
.amg-hero .amg-hero__top-section--has-image .amg-hero__hero-content-inner .amg-font-headline-1{font-size:var(--brand-primitives-channel-sizing-web-mobile-headline-3-font-size);line-height:var(--brand-primitives-channel-sizing-web-mobile-headline-3-leading)}
.amg-hero .amg-hero__actions-section .button a{max-width:90%;font-size:var(--brand-primitives-channel-sizing-web-mobile-headline-5-font-size);line-height:var(--brand-primitives-channel-sizing-web-mobile-body-2-leading)}
.amg-hero.inner-page-hero .amg-hero__hero-content.amg-hero__hero-content--align-left{background:0}
.amg-hero.inner-page-hero .amg-hero__top-section{aspect-ratio:2.5/1}
.amg-hero__content-card--no-bg .amg-hero__content-card-title{font-size:var(--typography-headings-intro-intro-2-font-size);line-height:var(--typography-headings-intro-intro-2-font-size-leading)}
}
.pie-chart-highlighting img.cmp-image__image{max-width:100%;width:37.5rem !important;margin:0 auto;padding-block:var(--spacing-primitives-spacing-48) var(--spacing-primitives-spacing-24)}
.lumakras-exp-img{padding-block:var(--spacing-primitives-spacing-40) var(--spacing-primitives-spacing-48)}
.lumakras-exp-img img{max-width:95%;margin:0 auto}
.study-design-graph{padding-top:var(--spacing-primitives-spacing-48)}
.objective-response-rate{padding-block:var(--spacing-primitives-spacing-40) var(--spacing-primitives-spacing-16)}
.objective-response-rate img.cmp-image__image{max-width:50.625rem;margin:0 auto}
.dose-yellow-tablet .amg-section-with-slots{max-width:47.1875rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.adverse-reaction-table-img{max-width:46.875rem;margin:0 auto}
.safety-population-img{max-width:43.125rem;margin:0 auto}
@media(max-width:767px){.study-design-graph{padding-top:var(--spacing-primitives-spacing-32)}
.study-design-graph img{max-width:85%;margin:0 auto}
.objective-response-rate{padding-top:var(--spacing-primitives-spacing-18)}
}
#jumplinks{border-bottom:var(--brand-primitives-borders-cards-regular-stroke-bottom) solid var(--brand-primitives-color-primary-dark-shade-2);background:var(--component-theme-light-surface-section-background-section-bg-3)}
#jumplinks .amg-nav__list{display:flex;width:100%;max-width:63.75rem}
#jumplinks .initial-section-header{padding-inline:0;max-width:63.75rem}
#jumplinks .amg-nav__list-item{max-width:fit-content;width:auto}
#jumplinks .amg-nav__list .amg-nav__link{width:max-content;max-width:max-content;font-weight:700;padding-right:var(--spacing-primitives-spacing-56);display:block;position:relative}
[id]:not(#indication){scroll-margin-top:-2rem !important}
#indication{scroll-margin-top:0rem !important}
amg-in-page-nav span.amg-nav__heading{padding-left:var(--spacing-primitives-spacing-12)}
amg-in-page-nav{padding-block:0}
amg-in-page-nav .amg-nav__list{display:grid;grid-row:2;gap:1rem;background:transparent;padding-inline:var(--spacing-primitives-spacing-12)}
amg-in-page-nav .amg-nav__list .amg-nav__link{border-radius:var(--brand-primitives-corner-radius-in-page-nav-radius-default);border:var(--borders-navigation-in-page-nav-minimal-underline) solid var(--component-theme-light-surface-interactive-navigation-in-page-nav-strong-outline-focus);background:var(--inpage-nav-gradient);width:100%;justify-content:space-between}
amg-in-page-nav .amg-nav__list .amg-nav__link amg-icon{color:var(--component-theme-light-surface-assets-secondary-base);position:absolute;right:var(--spacing-primitives-spacing-24);top:54.5%;transform:translateY(-50%)}
amg-in-page-nav .amg-nav__list .amg-nav__link:hover{background:var(--component-theme-light-surface-interactive-navigation-in-page-nav-strong-outline-focus);color:var(--component-theme-light-surface-static-text-icon-text-reversed)}
amg-in-page-nav .amg-nav__list .amg-nav__link--active{color:var(--component-theme-light-surface-interactive-base-low-prominence-text-icon-interactive)}
amg-in-page-nav .amg-nav{padding-block:var(--spacing-primitives-spacing-24);gap:var(--spacing-primitives-spacing-8);background:transparent;border:0;padding-inline:0}
amg-in-page-nav .amg-nav .amg-nav__label{grid-row:1;display:grid;border:0;padding-block:0}
.img-with-text{display:flex;flex-wrap:wrap;align-items:center;gap:var(--spacing-primitives-spacing-12)}
@media(max-width:61.9375rem){[id]:not(#indication){scroll-margin-top:-1.25rem !important}
amg-in-page-nav .amg-nav__list{gap:var(--spacing-primitives-spacing-16)}
amg-in-page-nav .amg-nav__list .amg-nav__link{justify-content:center;padding-block:var(--spacing-primitives-spacing-8)}
#jumplinks .amg-nav__toggle{display:none}
#jumplinks .amg-nav__heading{padding-left:var(--spacing-primitives-spacing-16)}
#jumplinks amg-in-page-nav{padding-inline:0}
#jumplinks .amg-nav{padding:0;padding-left:var(--spacing-primitives-spacing-16)}
#jumplinks .amg-nav__list{padding-left:0;display:flex;overflow-y:scroll}
#jumplinks .amg-nav__list .amg-nav__link{padding-inline:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-56)}
}
@media((min-width:47.9375rem) and (max-width:62rem)){#jumplinks .amg-nav{padding-bottom:0}
}
.safetytray-v2 amg-isi .amg-isi-container{max-width:100%;padding-top:1.25rem}
.safetytray-v2 amg-isi .amg-isi-container.tease{max-width:100%;background:var(--brand-primitives-color-neutral-light-base);transform:translate(-50%,20%) !important;padding-inline:var(--spacing-primitives-spacing-16);padding-top:0}
.safetytray-v2 amg-isi .amg-isi-container.tease .amg-isi-header.amg-py-comp-8{padding-block:var(--spacing-components-desktop-0) !important;max-width:76.875rem;margin:0 auto;justify-content:flex-start}
.safetytray-v2 amg-isi .amg-isi-container.tease .amg-isi-expand-btn{border-radius:0 0 var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-16);box-shadow:var(--btn-box-shadow);position:relative;top:-0.5rem;width:15.3125rem;padding-block:var(--spacing-primitives-spacing-12)}
.safetytray-v2 amg-isi .amg-isi-container.tease .amg-isi-expand-btn .amg-isi-expand-btn__label{font-size:var(--typography-headings-cta-large-font-size);font-weight:700}
.safetytray-v2 amg-isi .amg-isi-container.tease .amg-isi-expand-btn iconify-icon{font-size:var(--typography-headings-overline-1-font-size);font-weight:700}
.safetytray-v2 amg-isi .amg-isi-container.tease .amg-container{max-width:75rem !important;margin:0 auto;padding-inline:0}
.safetytray-v2 amg-isi .amg-isi-container.tease .amg-container.amg-isi-header-inner{padding-block:var(--spacing-components-desktop-0) !important}
.safetytray-v2 amg-isi .amg-isi-container .amg-isi-content-wrapper{padding:0 var(--spacing-primitives-spacing-16);max-width:74.375rem;margin:0 auto}
.safetytray-v2 amg-isi .amg-isi-container ul li{margin-left:var(--spacing-primitives-spacing-24);list-style:disc}
.safetytray-v2 amg-isi .amg-isi-container ul li::marker{color:var(--brand-primitives-color-section-section-bg-dark-1)}
.safetytray-v2 amg-isi .amg-isi-container .amg-isi-header-inner{padding:0 var(--spacing-primitives-spacing-16);max-width:74.375rem}
#isi{scroll-margin-top:11.25rem !important}
@media(max-width:767px){.safetytray-v2 amg-isi .amg-isi-container{padding-inline:var(--spacing-primitives-spacing-16);margin-inline:0}
.safetytray-v2 amg-isi .amg-isi-container.tease .amg-isi-expand-btn{width:8.4375rem;top:-0.75rem}
.safetytray-v2 amg-isi .amg-isi-container .amg-isi-content-wrapper,.safetytray-v2 amg-isi .amg-isi-container .amg-isi-header-inner{padding-inline:0}
}
.amg-references__list .amg-references__symbol{display:none}
.amg-references[aria-label="References Section"] .amg-container *{display:inline}
.referencesAndFootnotes .amg-references .amg-container{padding-inline:var(--spacing-primitives-spacing-16);max-width:74.375rem}
@media(max-width:767px){.referencesAndFootnotes .amg-references .amg-container{max-width:fit-content;width:90%}
.referencesAndFootnotes .amg-references .amg-references__content{width:100%}
}
.amg-section-header__bar{padding-block:var(--spacing-primitives-spacing-6)}
.sectionheader{background:var(--section-header-background-color);margin-block:var(--spacing-primitives-spacing-32)}
.sectionheader .amg-section-header{max-width:63.75rem;margin:0 auto}
.sectionheader .amg-section-header .amg-section-header__bar{padding-inline:var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-48);max-width:100%}
.sectionheader .amg-section-header .amg-section-header__title{padding-inline:0;text-align:left}
.sectionheader .amg-section-header .amg-section-header__title h3{margin-bottom:0;color:var(--brand-primitives-color-neutral-light-base)}
#discover .sectionheader{padding-top:var(--spacing-primitives-spacing-32);margin-top:0;background:var(--section-header-background-color-discover-page-discover-sec)}
@media((min-width:62.5rem) and (max-width:68.75rem)){#dosing .sectionheader{background:var(--section-header-background-color-dose-sec)}
#monitoring-menu .sectionheader{background:var(--section-header-background-color-dose-sec)}
}
@media((min-width:156.25rem) and (max-width:343.75rem)){.sectionheader{background:var(--section-header-background-color-large-screen)}
}
@media((min-width:157.5rem) and (max-width:237.5rem)){.sectionheader{background:var(--section-header-background-color-med-screen)}
}
@media(max-width:767px){.sectionheader{margin:var(--spacing-primitives-spacing-18) auto}
.sectionheader .amg-section-header .amg-section-header__bar{padding-inline:var(--spacing-primitives-spacing-16);display:block;max-width:90%}
#study-design-content{padding-top:var(--spacing-primitives-spacing-32)}
}
.amg-container.amg-stacks-container .amg-gap-comp-24 .amg-stack.amg-surface-light.amg-stack--padded{border-radius:var(--brand-primitives-corner-radius-cards-radius-cards-ul);border:solid var(--borders-weight-weight-1) var(--brand-primitives-color-primary-dark-base);background-image:var(--gradient-light-bg-gradient-with-opacity)}
.custome-ul-list{padding-top:0}
.custome-ul-list ul.amg-stack__bullet-list{gap:var(--spacing-primitives-spacing-8);list-style:none}
.custome-ul-list li.amg-stack__bullet-item{list-style:none}
.custome-ul-list li.amg-stack__bullet-item:before{background-image:url(data:image/svg+xml;base64,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);background-color:transparent;background-repeat:no-repeat;background-size:contain;position:absolute;top:.375rem;width:.75rem;height:.75rem}
.about-kras-footnote p{text-indent:-0.25rem}
.about-kras-footnote{padding-block:var(--brand-primitives-spacing-spacing-2) var(--brand-primitives-spacing-spacing-8);padding-inline:var(--brand-primitives-spacing-spacing-1)}
.about-kras-footnote p:last-child{text-indent:0}
.nccn-guideline-testing{border-radius:var(--brand-primitives-corner-radius-base-radius-base);background:var(--gradient-primary-bg-gradient-with-opacity) !important;margin-block:var(--spacing-primitives-spacing-10) var(--spacing-primitives-spacing-40);padding-inline:0;max-width:61.75rem}
.nccn-guideline-testing .inner-stack-nccn-guide{flex-direction:row;padding:var(--spacing-primitives-spacing-16);align-items:center;gap:var(--spacing-primitives-spacing-40)}
.nccn-guideline-testing .amg-stack__top{width:60%;align-self:center}
.nccn-guideline-testing .amg-stack__top img{width:11.875rem !important;height:auto !important}
.two-side-circle{position:relative;margin-block:var(--spacing-primitives-spacing-56) var(--spacing-primitives-spacing-32);border-radius:.25rem;border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-section-section-bg-dark-1);background:var(--component-theme-light-surface-section-background-section-bg-3);padding:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-40)}
.two-side-circle .amg-stack__content{text-align:center}
.two-side-circle:after{content:"";position:absolute;width:2.5rem;height:2.5rem;background-image:url(data:image/svg+xml;base64,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);background-color:transparent;background-repeat:no-repeat;background-size:contain;left:-1.25rem;top:50%;transform:translateY(-50%)}
.two-side-circle:before{content:"";position:absolute;width:2.5rem;height:2.5rem;background-image:url(data:image/svg+xml;base64,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);background-color:transparent;background-repeat:no-repeat;background-size:contain;top:50%;transform:translateY(-50%);right:-1.25rem}
.two-side-circle-cont .stacks{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.nccn-guide-line-grad-clr{background:var(--gradient-primary-bg-gradient-with-opacity) !important;padding-bottom:var(--spacing-primitives-spacing-48)}
.nccn-guide-stack{flex-direction:row;padding-block:var(--spacing-primitives-spacing-48) calc(var(--spacing-primitives-spacing-40) + var(--spacing-primitives-spacing-2));align-items:center;gap:var(--spacing-primitives-spacing-32)}
.nccn-guide-stack .amg-stack__top{width:60%}
.nccn-guide-footnote .amg-stack__body p{text-indent:calc(var(--spacing-primitives-spacing-6) * -1);padding-left:var(--spacing-primitives-spacing-8)}
.nccn-guide-footnote .amg-stack__body p:last-child{text-indent:0}
.is-desinged-inactive{padding-block:var(--spacing-primitives-spacing-32)}
.amg-supportplus .amg-section-with-slots{max-width:76.875rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content{align-items:center}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-01] .amg-stack__top .amg-content-icon__icon{width:25.9375rem;height:4.375rem}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-01] .amg-stack__content p .amg-font-headline-1{font-weight:var(--brand-primitives-typography-styles-body-base-weight);color:var(--brand-primitives-color-primary-dark-shade-1)}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-01] .amg-stack__body .amg-font-intro-2{color:var(--support-text-reveresd)}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-02] .amg-call-card{padding-block:calc(var(--spacing-primitives-spacing-40) + var(--spacing-primitives-spacing-2));border-radius:var(--brand-primitives-corner-radius-cards-radius-cards-ul)}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-02] .amg-call-card a.amg-btn{background:transparent;border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-neutral-light-base);color:var(--brand-primitives-color-neutral-light-base);padding-inline:var(--spacing-primitives-spacing-24)}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-02] .amg-call-card a.amg-btn:hover{background-color:var(--brand-primitives-color-primary-dark-base)}
.for-hcp-sec .amg-section-with-slots__content{max-width:76.875rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16);width:100%;gap:0}
.for-hcp-sec .amg-section-with-slots__content .amg-section-with-slots__content-block--1{border-right:var(--borders-weight-weight-2) solid var(--brand-primitives-color-section-section-bg-light-2);padding-right:var(--spacing-primitives-spacing-32)}
.for-hcp-sec .amg-section-with-slots__content .amg-section-with-slots__content-block--2{padding-left:var(--spacing-primitives-spacing-32)}
.for-hcp-stack.amg-stack{flex-direction:row;flex-wrap:wrap;justify-content:space-between}
.for-hcp-stack.amg-stack .amg-stack__top{max-width:15%}
.for-hcp-stack.amg-stack .amg-stack__content{max-width:80%}
.for-hcp-stack.amg-stack .amg-stack__content ul.benefits-list{list-style:disc;margin-left:var(--spacing-primitives-spacing-32);color:var(--brand-primitives-color-neutral-dark-base)}
.for-hcp-stack.amg-stack .amg-stack__actions{width:100%;justify-content:center}
.for-hcp-stack.amg-stack .amg-stack__actions a.amg-btn{color:var(--brand-primitives-color-primary-dark-shade-1);border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-primary-dark-shade-1)}
.for-hcp-stack.amg-stack .amg-stack__actions a.amg-btn:hover{color:var(--brand-primitives-color-neutral-light-base);border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-primary-dark-base)}
.for-hcp-stack.amg-stack .amg-stack__actions .button{transform:translateX(calc(var(--spacing-primitives-spacing-60) * -1))}
.for-hcp-stack.amg-stack .amg-stack__content h2{color:var(--brand-primitives-color-primary-dark-shade-1)}
.for-hcp-stack.amg-stack .amg-stack__content p{color:var(--support-text-reveresd);padding-block:var(--spacing-primitives-spacing-8)}
.financial-options-sec{background:var(--gradient-primary-bg-gradient-with-support) !important}
.financial-options-sec .commercial-insu{max-width:76.875rem;margin:var(--spacing-primitives-spacing-48) auto 0;padding-block:var(--spacing-primitives-spacing-56);padding-inline:var(--spacing-primitives-spacing-16)}
.financial-options-sec .commercial-insu .amg-stack__content h4{padding-bottom:var(--spacing-primitives-spacing-12)}
.financial-options-sec .commercial-insu .amg-stack__actions{padding-top:calc(var(--spacing-primitives-spacing-40) + var(--spacing-primitives-spacing-2))}
.financial-options-sec .commercial-insu .amg-stack__actions .amg-btn{background:transparent;border:var(--borders-weight-weight-2) solid var(--brand-primitives-color-neutral-light-base);color:var(--brand-primitives-color-neutral-light-base)}
.financial-options-sec .commercial-insu .amg-stack__actions .amg-btn:hover{background-image:var(--gradient-primary-bg-gradient-with-support-hover)}
.amg-for-patients-sec{max-width:76.875rem !important;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.amg-for-patients-sec .amg-stack.for-hcp-stack{gap:var(--spacing-primitives-spacing-18)}
.amg-for-patients-sec .amg-stack.for-hcp-stack .amg-stack__content{max-width:88%}
.amg-for-patients-sec .amg-stack.for-hcp-stack .amg-stack__top{max-width:10%}
.amg-for-patients-sec .sectionwithslots{padding-block:var(--spacing-primitives-spacing-56)}
.amg-for-patients-sec .sectionwithslots .amg-section-with-slots__content-block--1 .for-hcp-stack .amg-stack__content{max-width:84%}
.amg-for-patients-sec .sectionwithslots .amg-section-with-slots__content-block--1 .for-hcp-stack .amg-stack__actions .button{transform:translateX(-112%)}
.amg-for-patients-sec .sectionwithslots .amg-section-with-slots__content-block--2 .resource-icon{max-width:100%;width:100%}
.resource-page-stack{flex-direction:row;justify-content:space-between;gap:var(--spacing-primitives-spacing-24);align-items:center;padding:var(--spacing-primitives-spacing-24);border-bottom:.0625rem solid var(--card-bottom-line)}
.resource-page-stack .amg-stack__content{width:100%;gap:0}
.resource-page-stack .amg-stack__content .amg-font-headline-4{color:var(--brand-primitives-color-primary-dark-shade-1)}
.resource-page-stack .amg-stack__content .amg-font-body-1{color:var(--support-text-reveresd)}
.resource-page-stack .amg-stack__top{max-width:100%;width:15%}
.resource-page-stack .amg-stack__top img.amg-content-icon__icon{width:6rem;height:6rem}
.resource-page-stack .amg-stack__actions a.amg-btn{width:14.0625rem;padding-inline:var(--spacing-primitives-spacing-40);color:var(--brand-primitives-color-primary-dark-shade-1);border:.125rem solid var(--brand-primitives-color-primary-dark-shade-1);box-shadow:var(--btn-box-shadow);text-align:left}
.resource-page-stack .amg-stack__actions a.amg-btn amg-icon{right:2.375rem}
.resource-page-stack .office-tool-kit-btn .amg-btn{color:var(--brand-primitives-color-primary-dark-shade-1) !important;border:.125rem solid var(--brand-primitives-color-primary-dark-shade-1) !important}
.resource-page-stack .office-tool-kit-btn .amg-btn:hover{color:var(--brand-primitives-color-section-section-bg-light-1) !important;background-color:var(--brand-primitives-color-primary-dark-shade-1) !important}
.resource-page-stack .office-tool-kit-btn .amg-btn amg-icon iconify-icon{color:var(--brand-primitives-color-primary-dark-shade-1) !important}
.resource-page-stack .amg-stack__actions .cmp-button:not(.office-tool-kit-btn) a.amg-btn amg-icon iconify-icon{color:var(--brand-primitives-color-primary-dark-base) !important}
.other-helpfull-res .amg-stack__content .amg-text-primary{color:var(--brand-primitives-color-primary-dark-base)}
.other-helpfull-res .amg-stack__actions a.amg-btn{border:.125rem solid --brand-primitives-color-section-section-bg-dark-1;color:var(--brand-primitives-color-primary-dark-base)}
.resource-page-stack .amg-stack__actions a.amg-btn:hover{color:var(--brand-primitives-color-section-section-bg-light-1);border:.125rem solid --brand-primitives-color-section-section-bg-dark-1}
.resource-page-stack .amg-stack__actions a.amg-btn:hover amg-icon iconify-icon{color:var(--brand-primitives-color-section-section-bg-light-1) !important}
.other-helpfull-res .amg-stack__actions a.amg-btn:hover{color:var(--brand-primitives-color-section-section-bg-light-1)}
.other-helpfull-res .amg-stack__actions a.amg-btn:hover amg-icon iconify-icon{color:var(--brand-primitives-color-section-section-bg-light-1)}
.stacks:last-child .resource-page-stack{border-bottom:0}
.stacks:nth-child(5) .other-helpfull-res{border-bottom:0}
.key-baseline-list .amg-section-with-slots{max-width:63.75rem;margin:0 auto;padding:var(--spacing-primitives-spacing-32) var(--spacing-primitives-spacing-16)}
.key-baseline-list .amg-section-with-slots .amg-stack__body h5{padding-bottom:var(--spacing-primitives-spacing-12);position:relative;display:inline-block}
.key-baseline-list .amg-section-with-slots .amg-stack__body h5::after{content:"";background:var(--brand-primitives-color-accent-3-light-base);height:.125rem;position:absolute;bottom:0;left:0;width:108%;min-width:auto}
.key-baseline-list .amg-section-with-slots .amg-stack__body ul{padding-block:var(--spacing-primitives-spacing-12);margin-left:var(--spacing-primitives-spacing-4)}
.key-baseline-list .amg-section-with-slots .amg-stack__body ul li{padding-bottom:var(--spacing-primitives-spacing-6)}
.portion-of-codebreak p:first-child{text-indent:-0.3125rem}
.global-list-icon .amg-stack__bullet-item{padding-left:0}
.global-list-icon .amg-stack__bullet-list{padding-left:0}
.patinet-should-take{padding-block:var(--spacing-primitives-spacing-32);padding-left:var(--spacing-primitives-spacing-24)}
.dispreced-in-water{border-radius:var(--brand-primitives-corner-radius-base-radius-base);border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-system-info-light-base);padding:var(--spacing-primitives-spacing-32);margin-bottom:var(--spacing-primitives-spacing-32);max-width:61.625rem;background:var(--gradient-light-bg-gradient-with-opacity-reverse) !important}
.who-have-difficulty{flex-direction:row;gap:var(--spacing-primitives-spacing-24);padding-top:var(--spacing-primitives-spacing-32)}
.who-have-difficulty .amg-stack__top .amg-content-icon{width:7.8125rem;height:7.8125rem}
.who-have-difficulty .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-18);padding-top:var(--spacing-primitives-spacing-32);gap:var(--spacing-primitives-spacing-16)}
.missed-dose .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-24);gap:var(--spacing-primitives-spacing-8)}
.viral-homolog{padding-block:var(--spacing-primitives-spacing-8) var(--spacing-primitives-spacing-32)}
.error-page .amg-font-headline-1{font-size:8rem;font-weight:var(--brand-primitives-typography-styles-headings-emphasis-weight);line-height:1.13}
.error-page .amg-stack__actions .amg-btn{padding:var(--spacing-primitives-spacing-16) 3.125rem var(--spacing-primitives-spacing-16) 3.125rem !important;min-width:15.625rem;height:3.375rem;font-size:var(--typography-headings-cta-large-font-size);letter-spacing:var(--typography-headings-cta-large-letter-spacing)}
.error-page .amg-stack__actions .amg-btn amg-icon{right:auto !important;left:1.5625rem}
.sitemap h2{font-size:2.25rem;line-height:2.5rem}
.sitemap .text a{text-decoration:none;border-bottom:.0625rem solid var(--brand-primitives-color-primary-dark-base);line-height:3.125rem;font-size:var(--typography-headings-body-body-1-font-size)}
.sitemap p sup{font-weight:700}
.pl-15{margin-left:.9375rem}
#discover-support{max-width:100%}
.dosing-resource .amg-stack__top .amg-content-icon{width:6rem;height:6rem}
.dose-steps .amg-section-with-slots{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16);align-items:center}
.dose-steps .amg-section-with-slots .amg-section-with-slots__content{align-items:center;padding-block:var(--spacing-primitives-spacing-48);gap:0}
.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--1,.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--3,.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--5{width:20.3125rem}
.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--2,.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--4{width:0rem}
.dose-modii-list .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-20);padding-top:var(--spacing-primitives-spacing-8)}
.accordion-sublist .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-20);gap:var(--spacing-primitives-spacing-8)}
.accordion-sublist .amg-stack__bullet-list p + ul li{padding-left:0;margin-left:var(--spacing-primitives-spacing-4);gap:var(--spacing-primitives-spacing-8)}
.accordion-sublist .amg-stack__bullet-list .amg-stack__bullet-item{gap:var(--spacing-primitives-spacing-12)}
.accordion-sublist .amg-stack__bullet-list .amg-stack__bullet-item ul{margin-top:0}
.accordion-sublist .amg-stack__bullet-list .amg-stack__bullet-item ul li{margin-bottom:0}
.coadministration-sec{padding-block:var(--spacing-primitives-spacing-16) var(--spacing-primitives-spacing-32)}
.coadministration-list{padding-left:var(--spacing-primitives-spacing-20)}
.safety-conderation{padding-block:var(--spacing-primitives-spacing-32)}
.safety-consider-percent{border-radius:var(--brand-primitives-corner-radius-base-radius-base);background:var(--gradient-primary-bg-gradient-with-opacity) !important;padding-block:var(--spacing-primitives-spacing-32);margin-bottom:var(--spacing-primitives-spacing-48);max-width:61.625rem}
.safety-consider-percent .safety-stack-percent{flex-direction:row;align-items:center;padding-block:var(--spacing-primitives-spacing-18);max-width:53.75rem;margin:0 auto;justify-content:space-between;padding-inline:0}
.safety-consider-percent .safety-stack-percent .amg-stack__top .safety-data-number{width:12.5rem;justify-content:flex-end}
.safety-consider-percent .safety-stack-percent .amg-stack__top .safety-data-number span{color:var(--component-theme-light-surface-static-text-icon-text-reversed);font-weight:600}
.safety-consider-percent .safety-stack-percent .amg-stack__content{width:39.6875rem}
.safety-consider-percent .safety-stack-percent .amg-stack__content h4{padding-bottom:var(--spacing-primitives-spacing-8)}
.safety-consider-percent .safety-stack-percent .amg-stack__content h4 + p{padding-top:var(--spacing-primitives-spacing-8);border-top:var(--borders-weight-weight-1) solid var(--brand-primitives-color-neutral-light-alpha-24)}
.use-of-antiematic{padding-bottom:var(--spacing-primitives-spacing-32)}
.use-of-antiematic .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-20)}
.select-antiametic-list .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-20)}
.monitering-head-sec{padding-bottom:var(--spacing-primitives-spacing-32)}
.hepatotoxicity{padding-bottom:var(--spacing-primitives-spacing-16)}
.liver-monitoring-sec{max-width:61.625rem;margin:0 auto;border-radius:var(--brand-primitives-corner-radius-base-radius-inside);border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-primary-dark-base);background:var(--gradient-light-bg-gradient-with-opacity-reverse) !important;padding:var(--spacing-primitives-spacing-32) var(--spacing-primitives-spacing-56)}
.liver-monitoring-sec .text{padding-bottom:var(--spacing-primitives-spacing-32);max-width:52.1875rem;margin:0 auto}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content{align-items:center;max-width:52.1875rem;margin:0 auto;gap:var(--spacing-primitives-spacing-24)}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--2{width:5rem}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--1 .hepatotoxicity-section-one{flex-direction:row}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--1 .hepatotoxicity-section-one .amg-stack__content{text-align:left}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--1 .hepatotoxicity-section-one .amg-stack__top{width:3.3125rem}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--3 .amg-stack__content{text-align:left}
.pneumonitis-list{padding-top:var(--spacing-primitives-spacing-32)}
.ild-pneumonitis{margin-top:var(--spacing-primitives-spacing-32)}
.ild-pneumonitis .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-20)}
.for-more-pre{max-width:54.6875rem;margin:var(--spacing-primitives-spacing-32) auto 0}
.for-more-pre .amg-stack__body a{color:var(--brand-primitives-color-section-section-bg-dark-1)}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content{max-width:51.875rem;margin:0 auto;gap:0}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content .amg-stack__bullet-list{gap:var(--spacing-primitives-spacing-32)}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content .amg-stack__bullet-list>.amg-stack__bullet-item:before{content:none}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content .amg-stack__bullet-list h5{border-bottom:var(--borders-weight-weight-2) solid var(--brand-primitives-color-accent-3-light-base);padding-bottom:var(--spacing-primitives-spacing-6)}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content .amg-stack__bullet-list .amg-stack__bullet-nested{padding-left:var(--spacing-primitives-spacing-20);gap:var(--spacing-primitives-spacing-8)}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content .amg-stack__bullet-list .amg-stack__bullet-nested .amg-stack__bullet-item:before{top:var(--spacing-primitives-spacing-12)}
.safety-analysis-sec h2,.safety-analysis-sec h3,.safety-analysis-sec p{padding-bottom:var(--spacing-primitives-spacing-24)}
.study-population .amg-stack__bullet-list>.amg-stack__bullet-item{display:block}
.study-population .amg-stack__bullet-list>.amg-stack__bullet-item:before{content:none}
.study-population .amg-stack__bullet-list>.amg-stack__bullet-item>p{padding-bottom:var(--spacing-primitives-spacing-8);border-bottom:var(--borders-weight-weight-2) solid var(--brand-primitives-color-accent-3-light-base)}
.study-population .amg-stack__bullet-nested{padding-top:var(--spacing-primitives-spacing-8);padding-left:var(--spacing-primitives-spacing-20);gap:var(--spacing-primitives-spacing-8)}
.study-population .amg-stack__bullet-nested .amg-stack__bullet-item:before{top:var(--spacing-primitives-spacing-12)}
.patient-with-ecog{padding-block:var(--spacing-primitives-spacing-24);text-align:center}
.patient-with-ecog-image{max-width:43.125rem;margin:0 auto}
.score-of-ecog{max-width:55.625rem;margin:var(--spacing-primitives-spacing-24) auto}
.hepatotoxicity-text h3{padding-bottom:var(--spacing-primitives-spacing-8)}
.hepatotoxicity-list{padding-left:var(--spacing-primitives-spacing-20);padding-block:var(--spacing-primitives-spacing-32)}
.hepatotoxicity-list .amg-stack__bullet-list{gap:var(--spacing-primitives-spacing-16)}
.hepatotoxicity-list .amg-stack__bullet-list>li{gap:var(--spacing-primitives-spacing-16);padding-bottom:0;margin:0}
.hepatotoxicity-list .amg-stack__bullet-list ul{margin-top:0;padding-left:var(--spacing-primitives-spacing-20)}
.hepatotoxicity-list .amg-stack__bullet-list ul li{padding-left:0;margin-bottom:0}
.among-patients{padding-left:var(--spacing-primitives-spacing-20)}
.safety-ILD-pneumonitis h3{padding-block:var(--spacing-primitives-spacing-18) var(--spacing-primitives-spacing-8)}
.safety-ILD-pneumonitis .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-20);padding-block:var(--spacing-primitives-spacing-12)}
.gastrointestinal-text h3{padding-bottom:var(--spacing-primitives-spacing-8)}
.gastrointestinal-text p{padding-bottom:var(--spacing-primitives-spacing-24)}
.safety-patients-experiencing{text-align:center;padding-bottom:var(--spacing-primitives-spacing-28)}
.safety-patients-experiencing-img{max-width:39.375rem;margin:0 auto;padding-bottom:var(--spacing-primitives-spacing-32)}
.safety-patients-experiencing-list{padding-left:var(--spacing-primitives-spacing-20)}
.safety-patinet-exp-foot{padding-top:var(--spacing-primitives-spacing-0)}
.safety-patinet-exp-foot p:last-child{text-indent:calc(var(--spacing-primitives-spacing-14) * -1)}
.recommended-dosage{max-width:55.9375rem;margin:var(--spacing-primitives-spacing-32) auto}
.recommend-foot{padding:var(--spacing-primitives-spacing-0)}
.orphan-nccn .amg-stack{flex-wrap:wrap}
.orphan-nccn .amg-stack .amg-stack__top{width:20%}
.orphan-nccn .amg-stack .amg-stack__content{width:70%}
.orphan-nccn .amg-stack .amg-stack__actions{transform:translateX(110%)}
.orphan-nccn .amg-stack .amg-stack__actions a iconify-icon{font-size:.625rem !important}
@media(max-width:767px){.orphan-nccn .amg-stack{flex-direction:column;display:flex;gap:1.25rem}
.orphan-nccn .amg-stack .amg-card__content{gap:var(--spacing-primitives-spacing-24);width:100%}
.orphan-nccn .amg-stack .amg-stack__top{width:auto}
.orphan-nccn .amg-stack .amg-stack__actions{transform:none}
.orphan-nccn .amg-stack .amg-stack__actions a{width:12.5rem}
.orphan-nccn .amg-stack .amg-stack__content{width:100%}
}
.orphan-text h2,.orphan-text h2 span{font-size:1.875rem}
@media(min-width:48rem) and (max-width:64rem){.liver-monitoring-sec{max-width:96%}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content{max-width:100%}
.safety-consider-percent{max-width:96%}
}
@media(min-width:48rem) and (max-width:61.9375rem){.amg-for-patients-sec .sectionwithslots .amg-section-with-slots__content-block--1 .for-hcp-stack .amg-stack__actions .button{transform:translateY(-25%)}
.amg-for-patients-sec .amg-stack.for-hcp-stack .amg-stack__top{max-width:fit-content}
}
@media(max-width:767px){.nccn-guideline-testing{margin-inline:var(--spacing-primitives-spacing-16)}
.nccn-guideline-testing .inner-stack-nccn-guide{flex-direction:column;justify-content:center;align-items:center;gap:0}
.nccn-guideline-testing .amg-stack__top{width:100%}
.two-side-circle{padding:var(--spacing-primitives-spacing-18)}
.call-your-lab-container .stacks,.keep-test-result .stacks{margin-inline:var(--spacing-primitives-spacing-16)}
.nccn-guide-stack{flex-direction:column;padding-block:0 var(--spacing-primitives-spacing-28);gap:0}
.nccn-guide-stack .amg-stack__top{margin:0 auto}
.for-hcp-stack.amg-stack{flex-direction:column;gap:var(--spacing-primitives-spacing-24)}
.for-hcp-stack.amg-stack .amg-stack__top{max-width:100%;margin:auto}
.for-hcp-stack.amg-stack .amg-stack__content{max-width:100%}
.for-hcp-stack.amg-stack .amg-stack__content h2{text-align:center}
.for-hcp-stack.amg-stack .amg-stack__actions .button{transform:none}
.for-hcp-stack.amg-stack .amg-stack__actions a.amg-btn{padding-block:var(--spacing-primitives-spacing-18)}
.resource-page-stack{flex-direction:column;padding-inline:0}
.resource-page-stack .amg-stack__top{margin:auto;width:100%}
.resource-page-stack .amg-stack__content{text-align:center;gap:var(--spacing-primitives-spacing-10)}
.key-baseline-list .amg-section-with-slots{padding-bottom:0}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-02] .amg-call-card{padding-block:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-32);padding-inline:var(--spacing-primitives-spacing-16)}
.amg-supportplus .amg-section-with-slots .amg-section-with-slots__content [slot=content-block-02] .amg-call-card .amg-stack__body p:first-child{padding-bottom:var(--spacing-primitives-spacing-12)}
.for-hcp-stack.amg-stack .amg-stack__actions{display:block}
.for-hcp-stack.amg-stack .amg-stack__actions a{width:100%}
.amg-for-patients-sec .amg-stack.for-hcp-stack .amg-stack__top{max-width:100%}
.amg-for-patients-sec .amg-stack.for-hcp-stack .amg-stack__content{max-width:100%}
.amg-for-patients-sec .sectionwithslots{padding-block:var(--spacing-primitives-spacing-16)}
.amg-for-patients-sec .sectionwithslots .amg-section-with-slots__content-block--1 .for-hcp-stack .amg-stack__actions .button{transform:none;padding-block:var(--spacing-primitives-spacing-16)}
.amg-for-patients-sec .sectionwithslots .amg-section-with-slots__content-block--1 .for-hcp-stack .amg-stack__content{max-width:100%}
.financial-options-sec .commercial-insu .amg-stack__actions{padding-top:var(--spacing-primitives-spacing-18)}
.for-hcp-sec .amg-section-with-slots__content{padding-inline:0}
.for-hcp-sec .amg-section-with-slots__content .amg-section-with-slots__content-block--1{border-bottom:var(--brand-primitives-borders-weight-weight-2) solid var(--brand-primitives-color-neutral-light-tint-3);padding-bottom:var(--spacing-primitives-spacing-24);padding-inline:0;border-right:0}
.for-hcp-sec .amg-section-with-slots__content .amg-section-with-slots__content-block--2{padding-left:0}
.key-baseline-list .amg-section-with-slots .amg-stack__body h5{display:block}
.key-baseline-list .amg-section-with-slots .amg-stack__body h5::after{width:100%}
.who-have-difficulty{flex-direction:column;padding-top:var(--spacing-primitives-spacing-16)}
.who-have-difficulty .amg-stack__top{align-self:center}
.who-have-difficulty .amg-stack__top .amg-content-icon{width:5.625rem;height:5.625rem}
.dispreced-in-water{padding:var(--spacing-primitives-spacing-16)}
.dose-steps .amg-section-with-slots .amg-section-with-slots__content{align-items:center;padding-block:var(--spacing-primitives-spacing-48);gap:var(--spacing-primitives-spacing-32)}
.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--2,.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--4{width:0rem;margin-inline:auto}
.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--2 .amg-content-icon,.dose-steps .amg-section-with-slots .amg-section-with-slots__content .amg-section-with-slots__content-block--4 .amg-content-icon{transform:rotate(90deg);width:3.75rem}
.safety-consider-percent{max-width:90%;padding-block:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-40);border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-section-section-bg-dark-)}
.safety-consider-percent .safety-stack-percent{max-width:100%;flex-direction:column;padding-block:var(--spacing-primitives-spacing-8);text-align:center}
.safety-consider-percent .safety-stack-percent .amg-stack__top{align-self:center}
.safety-consider-percent .safety-stack-percent .amg-stack__content{width:100%}
.safety-consider-percent .safety-stack-percent .amg-stack__top .safety-data-number{width:100%}
.monitering-head-sec{padding-bottom:var(--spacing-primitives-spacing-24)}
.liver-monitoring-sec{max-width:90%;padding:var(--spacing-primitives-spacing-32)}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content{max-width:100%}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--1 .hepatotoxicity-section-one{flex-direction:column;width:100%}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--2{width:100%}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--2 .amg-content-icon{transform:rotate(90deg)}
.liver-monitoring-sec .sectionwithslots .amg-section-with-slots__content .amg-section-with-slots__content-block--3 .amg-stack__content{text-align:center}
.for-more-pre{max-width:85%}
.additional-baseline-char .amg-section-with-slots{padding-inline:0}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content .amg-stack__bullet-list{gap:var(--spacing-primitives-spacing-24)}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content{max-width:100%}
.additional-baseline-char .amg-section-with-slots .amg-section-with-slots__content-block--1{padding-bottom:var(--spacing-primitives-spacing-24)}
.pneumonitis-list{padding:var(--spacing-primitives-spacing-16) 0 0}
.error-page .amg-stack__actions{margin-inline:auto;padding-top:var(--spacing-primitives-spacing-24)}
.error-page .amg-stack__actions a.amg-btn{min-width:fit-content}
}
.about-kras-table{max-width:56.25rem;margin:0 auto;padding-bottom:var(--spacing-primitives-spacing-24)}
.about-kras-table table.amg-table{max-width:46.875rem;margin-left:auto}
.about-kras-table table thead tr th{border:0;border-bottom:var(--borders-weight-weight-2) solid var(--brand-primitives-color-accent-3-light-base);width:revert;text-align:center;max-width:25%}
.about-kras-table table thead tr th:nth-child(2){width:revert-layer;max-width:5%}
.about-kras-table table thead tr th:nth-child(3){width:revert-layer;max-width:5%}
.about-kras-table table thead tr th:nth-child(4){width:revert-layer;vertical-align:middle;max-width:10%}
.about-kras-table table thead tr:nth-child(3) th{width:.625rem}
.about-kras-table table tbody tr td{border:0;border-bottom:var(--borders-weight-weight-2) solid var(--brand-primitives-color-accent-3-light-base);text-align:center}
.about-kras-table table tbody tr:last-child td{border-bottom:0}
@media(max-width:767px){.about-kras-table{padding-block:var(--spacing-primitives-spacing-32) var(--spacing-primitives-spacing-24);margin-inline:var(--spacing-primitives-spacing-16)}
.amg-table__container td .amg-font-body-1{font-size:var(--typography-headings-overline-2-font-size);line-height:normal}
.about-kras-table table thead tr .amg-font-headline-6{font-size:var(--typography-headings-overline-2-font-size)}
.about-kras-table table tbody tr td{padding-inline:0}
.about-kras-table table thead tr th{padding-inline:0}
}
.amg-tab--low.amg-tab--minimal .amg-tab__tab-list{background:var(--brand-primitives-color-neutral-dark-alpha-8);gap:var(--spacing-primitives-spacing-12);justify-content:center;border-radius:var(--brand-primitives-corner-radius-base-radius-circular);padding:var(--spacing-primitives-spacing-4) var(--spacing-primitives-spacing-10)}
@media(max-width:767px){.amg-tab--low.amg-tab--minimal .amg-tab__tab-list{gap:var(--spacing-primitives-spacing-8);flex-wrap:wrap;background:0}
}
.amg-tab--low.amg-tab--minimal .amg-tab__tab-list .amg-tab__tab-button.is-active,.amg-tab--low.amg-tab--minimal .amg-tab__tab-list .amg-tab__tab-button:hover{border-radius:var(--brand-primitives-corner-radius-tabs-tabs-alt);border:var(--spacing-primitives-spacing-2) solid var(--brand-primitives-color-section-section-bg-light-1);background:var(--brand-primitives-color-section-section-bg-dark-1);box-shadow:0 var(--spacing-primitives-spacing-4) var(--spacing-primitives-spacing-4) var(--brand-primitives-color-neutral-dark-alpha-24);color:var(--brand-primitives-color-section-section-bg-light-1);opacity:1}
.amg-tab--low.amg-tab--minimal .amg-tab__tab-list .amg-tab__tab-button{border-radius:var(--brand-primitives-corner-radius-tabs-tabs-alt);border:var(--spacing-primitives-spacing-2) solid var(--brand-primitives-color-section-section-bg-light-1);opacity:.5;background:var(--brand-primitives-color-neutral-dark-base);box-shadow:0 var(--spacing-primitives-spacing-4) var(--spacing-primitives-spacing-4) 0 var(--brand-primitives-color-neutral-dark-alpha-24);color:var(--brand-primitives-color-section-section-bg-light-1);padding-block:var(--spacing-primitives-spacing-12);width:50%}
@media(max-width:767px){.amg-tab--low.amg-tab--minimal .amg-tab__tab-list .amg-tab__tab-button{width:100%}
}
.amg-tab--low.amg-tab--minimal .amg-tab__tab-list .amg-tab__tab-button .amg-tab__tab-text{align-items:center}
.amg-tab.amg-tab--low.amg-tab--no-elevation .amg-tab__tab-list .amg-tab__tab-button.is-active + .amg-tab__tab-button,.amg-tab.amg-tab--low.amg-tab--no-elevation .amg-tab__tab-list .amg-tab__tab-button.is-active{border-inline:none}
.global-tab-btn .amg-tab__content-container{padding:0}
.global-tab-btn .amg-tab__tab-bar{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16)}
.global-tab-btn .amg-tab__tab-bar .amg-tab__tab-button{pointer-events:none;box-shadow:var(--btn-box-shadow);border:var(--brand-primitives-borders-tabs-alt-stroke-active) solid var(--component-theme-light-surface-section-background-section-bg-2)}
.global-tab-btn .amg-tab__tab-bar .amg-tab__tab-button:hover{background:var(--brand-primitives-color-section-section-bg-dark-1)}
#three-year-orr-tabs .amg-tab{max-width:63.75rem;margin:0 auto;padding-inline:var(--spacing-primitives-spacing-16);padding-top:var(--spacing-primitives-spacing-32)}
#three-year-orr-tabs .amg-tab .amg-tab__tab-list{gap:var(--spacing-primitives-spacing-16);background:var(--brand-primitives-color-neutral-light-tint-2);padding:var(--spacing-primitives-spacing-6)}
#three-year-orr-tabs .amg-tab .amg-tab__tab-list .amg-tab__tab-button{box-shadow:var(--btn-box-shadow);border:var(--borders-weight-weight-1) solid;background:var(--tabs-background-clr)}
#three-year-orr-tabs .amg-tab .amg-tab__tab-list .amg-tab__tab-button:hover{background:var(--brand-primitives-color-interactive-light-2);color:var(--brand-primitives-color-section-section-bg-light-1);border:var(--borders-weight-weight-1) solid var(--brand-primitives-color-interactive-light-2)}
#three-year-orr-tabs .amg-tab .amg-tab__tab-list .amg-tab__tab-button.is-active{background-color:var(--brand-primitives-color-interactive-light-2)}
#three-year-orr-tabs .amg-tab .amg-tab__tab-list .amg-tab__tab-button.is-active:hover{border-color:var(--brand-primitives-color-interactive-light-1)}
#three-year-orr-tabs .amg-tab__content-container{padding:0}
.imp-consider{padding-top:var(--spacing-primitives-spacing-32)}
.imp-consider h5{padding-bottom:var(--spacing-primitives-spacing-8)}
.imp-consider ul{list-style:none !important;margin-left:var(--spacing-primitives-spacing-18)}
#efficacy-uspi-tabs .amg-tab__tab-list{padding:0}
@media(max-width:767px){#three-year-orr-tabs .inner-page-width{padding-inline:0}
#three-year-orr-tabs .amg-tab .amg-tab__tab-list{flex-direction:column;background:transparent}
#three-year-orr-tabs .amg-tab .amg-tab__tab-list .amg-tab__tab-button{box-shadow:var(--btn-box-shadow);border:var(--brand-primitives-borders-tabs-alt-stroke-active) solid var(--component-theme-light-surface-section-background-section-bg-2)}
#three-year-orr-tabs ul{margin-left:1.25rem}
#efficacy-uspi-tabs .amg-tab{gap:var(--spacing-primitives-spacing-32)}
}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .cmp-adaptiveform-container__wrapper>.text.base .stay-connected,.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .signup-today{font-size:var(--typography-headings-body-body-1-font-size);font-weight:700;color:var(--component-theme-light-surface-interactive-forms-outline-default)}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .cmp-adaptiveform-container__wrapper>.text.base + .text.base div>div{border-radius:var(--brand-primitives-corner-radius-base-radius-inside);background:var(--component-theme-light-surface-section-background-section-bg-2);padding:var(--spacing-primitives-spacing-14) var(--spacing-primitives-spacing-24);max-width:86%;margin-block:var(--spacing-primitives-spacing-24)}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .cmp-adaptiveform-container__wrapper>.text.base + .text.base div p{font-size:var(--typography-headings-body-body-1-font-size);color:var(--component-theme-light-surface-interactive-forms-outline-default);padding-bottom:0}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .cmp-adaptiveform-container__wrapper>.text.base + .text.base div p.mt-4{margin-top:var(--spacing-primitives-spacing-16) !important}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .cmp-adaptiveform-container__wrapper>.text.base + .text.base div p + p + p{display:none}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .cmp-adaptiveform-container__wrapper>.text.base + .text.base div p.mt-4 a{font-size:var(--typography-headings-body-body-1-font-size);color:var(--component-theme-light-surface-interactive-forms-outline-default);padding-bottom:0}
.bio-marker-testing{padding-bottom:var(--spacing-primitives-spacing-32)}
.testing-for-kras-footnote p{text-indent:-0.375rem;padding-left:.375rem}
.testing-for-kras-footnote p:nth-child(5){text-indent:-0.75rem}
.testing-for-kras-footnote p:nth-child(6){text-indent:-0.5rem;padding-left:.5rem}
.testing-for-kras-footnote p:last-child{text-indent:-0.5rem;padding-left:.625rem}
.stay-connected .signup-today{display:block;margin-top:var(--spacing-primitives-spacing-16)}
.lumakras-exp-footnote p{text-indent:calc(var(--spacing-primitives-spacing-6) * -1);padding-bottom:var(--spacing-primitives-spacing-4);padding-left:var(--spacing-primitives-spacing-8)}
.lumakras-exp-footnote p:nth-child(5){text-indent:calc(var(--spacing-primitives-spacing-10) * -1);padding-left:var(--spacing-primitives-spacing-10)}
.lumakras-exp-footnote p:nth-child(4){text-indent:calc(var(--spacing-primitives-spacing-12) * -1);padding-left:var(--spacing-primitives-spacing-8)}
.lumakras-exp-footnote p:last-child{text-indent:var(--spacing-primitives-spacing-0)}
.lumakras-exp-footnote{padding-bottom:var(--spacing-primitives-spacing-48)}
.home-footnote p{text-indent:-0.3125rem;padding-left:var(--spacing-primitives-spacing-8)}
.testing-for-kras-footnote{padding-left:var(--spacing-primitives-spacing-32)}
.about-kras-footnote{padding-left:var(--spacing-primitives-spacing-4)}
.portion-of-codebreak{padding-bottom:var(--spacing-primitives-spacing-32)}
#number-of-patients{margin-top:var(--spacing-primitives-spacing-56)}
.code-break-single{padding-top:0}
.for-hcp-container .sectionwithslots + .responsivegrid .cmp-text{padding-top:var(--spacing-primitives-spacing-16)}
.dose-modi-footnote{padding-block:var(--spacing-primitives-spacing-28) var(--spacing-primitives-spacing-16)}
.adverse-reaction-table-head{max-width:50.625rem;padding-block:var(--spacing-primitives-spacing-48) var(--spacing-primitives-spacing-32)}
.pooled-safety h5{padding-bottom:var(--spacing-primitives-spacing-12)}
.pooled-safety-list .amg-stack__bullet-list{padding-left:var(--spacing-primitives-spacing-20)}
.pooled-safety-list{padding-block:var(--spacing-primitives-spacing-18)}
.unacceptable-toxicit{padding-bottom:var(--spacing-primitives-spacing-32)}
.safety-population-text{text-align:center;padding-block:var(--spacing-primitives-spacing-32)}
.expanded-access-pgm{padding-bottom:var(--spacing-primitives-spacing-32)}
.expanded-access-pgm h4{padding-bottom:var(--spacing-primitives-spacing-24)}
.adeverse-reaction-sec-footnote p{padding-left:var(--spacing-primitives-spacing-16)}
.adeverse-reaction-sec-footnote p:nth-child(5),.adeverse-reaction-sec-footnote p:nth-child(6),.adeverse-reaction-sec-footnote p:nth-child(7),.adeverse-reaction-sec-footnote p:nth-child(8){text-indent:-0.75rem}
.adeverse-reaction-sec-footnote p:last-child{text-indent:-0.75rem}
.adeverse-reaction-sec-footnote p:nth-child(9){text-indent:-1.25rem}
.efficacy-study-population{display:flex;flex-wrap:wrap;justify-content:space-between;max-width:100%;column-gap:var(--spacing-primitives-spacing-0);margin-block:var(--spacing-primitives-spacing-40) var(--spacing-primitives-spacing-24);row-gap:var(--spacing-primitives-spacing-16)}
.efficacy-study-population .item{max-width:48%;width:100%}
.efficacy-study-population .item ul{list-style:none !important;margin-left:var(--spacing-primitives-spacing-20);padding-top:var(--spacing-primitives-spacing-12)}
.efficacy-study-population .item h3{padding-bottom:var(--spacing-primitives-spacing-12)}
.efficacy-study-population .item ul li{padding-bottom:var(--spacing-primitives-spacing-6)}
.efficacy-study-population .item h5{position:relative;display:inline-block;padding-bottom:var(--spacing-primitives-spacing-12)}
.efficacy-study-population .item h5:after{content:"";background:var(--brand-primitives-color-accent-3-light-base);height:var(--borders-weight-weight-2);position:absolute;bottom:0;left:0;width:108%;min-width:auto}
@media(max-width:767px){.home-footnote p{text-indent:-0.3125rem;padding-left:var(--spacing-primitives-spacing-4)}
.form-top-sec .text .note-to-users{max-width:100%}
.connect-with-amgen .container.aem-GridColumn--default--12 .connect-with-rep .connect-with-rep-form .cmp-adaptiveform-container__wrapper>.text.base + .text.base div>div{max-width:100%}
#number-of-patients{margin-top:var(--spacing-primitives-spacing-12)}
#three-year-orr-tabs .amg-tab__content-container .cmp-text{padding-block:var(--spacing-primitives-spacing-24) var(--spacing-primitives-spacing-12)}
.first-trail p:last-child{padding-top:var(--spacing-primitives-spacing-16)}
.key-baseline{padding-top:var(--spacing-primitives-spacing-32)}
.adverse-reaction-table-head{max-width:100%;padding-block:var(--spacing-primitives-spacing-24)}
.safety-population-text{padding-top:0}
.efficacy-study-population .item{max-width:100%}
.efficacy-study-population .item h5{display:block}
.efficacy-study-population .item h5:after{width:100%}
}
}
:root{--primary-1:#343434;--primary-4:#fafafa;--secondary-1:#c62424;--tertiary-1:#737373;--secondary-2:#000;--tertiary-2:#4b4b4b;--tertiary-3:rgba(21,21,21,0.3);--tertiary-20:rgba(0,0,0,0.2);--bg-grey:#f3f3f3;--bg-dark-blue:#004061;--linear-gradient-1:linear-gradient(41deg,#0063c3 0,#00bce4 100%);--amgen-blue:#0063c3;--actimmune-green:#78be20}
@keyframes fadeInUp{from{opacity:0;transform:translate3d(0,100%,0)}
to{opacity:1;transform:translate3d(0,0,0)}
}
@keyframes fadeUpIn{from{opacity:0;transform:translate3d(0,100%,0)}
to{opacity:1;transform:translate3d(0,0,0)}
}
:root{--error:#f44336}
.container{width:100%}
@media(min-width:576px){.container{max-width:33.75rem}
}
@media(min-width:768px){.container{max-width:45rem}
}
@media(min-width:992px){.container{max-width:60rem}
}
@media(min-width:1200px){.container{max-width:71.25rem}
}
@media(min-width:1400px){.container{max-width:85.625rem}
}
@media(min-width:1500px){.container{max-width:91.875rem}
}
@media(min-width:1700px){.container{max-width:104.5rem}
}
[id]{scroll-margin-top:9rem !important}
@media(max-width:1399.98px){[id]{scroll-margin-top:7.5rem !important}
}
@media(max-width:1199.98px){[id]{scroll-margin-top:5.625rem !important}
}
@media(max-width:991.98px){[id]{scroll-margin-top:6.563rem !important}
}
@media(max-width:767.98px){[id]{scroll-margin-top:5.063rem !important}
}
@media(min-width:93.75rem){.content-body,.content-body .cmp-container{max-width:93.875rem !important}
}
.content-body{padding-left:var(--grid-foundations-outer-margin);padding-right:var(--grid-foundations-outer-margin)}